Tests Mlambe to reduce heavy drinking in married couples in Malawi affected by HIV
Tests Mlambe, a savings and relationship program, in HIV-affected married couples where one partner drinks.
Plain-language title generated from the registry record
Registry title: An Economic and Relationship-strengthening Intervention to Reduce Alcohol Use in Malawi
Key facts
- Where
- Zomba, MalawiSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for married or living-together couples in Malawi who are affected by HIV. At least one partner drinks alcohol heavily.
- Age
- 18 years or older
- Sex
- Men and women
- Disease stage
- At least one partner had a positive AUDIT-C alcohol screen in the past 3 months.
- Earlier treatment
- Must be on ART (HIV treatment) for at least 6 months.
Main reasons for not taking part
- Severe intimate partner violence in the past 3 months
- Fear that taking part would put safety at risk
- Took part in Mlambe's pilot study
Read by machine on 9 November 2026.
Where in Malawi
- Invest in Knowledge Initiative (IKI)Zomba, MalawiTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University of California, San Francisco
- Trial code
- NCT06367348
- Record updated
- 14 May 2026
- Original description
With a full-scale randomized control trial, the investigators will evaluate the efficacy and cost effectiveness of Mlambe, an economic and relationship-strengthening intervention that provides incentivized saving accounts, financial literacy training, and relationship skills education to break the cycle of poverty around drinking, strengthen couple support and communication, and reduce heavy drinking among HIV-affected married couples with a partner who drinks alcohol in Malawi.Read full original descriptionShow less
Mlambe: A Randomized Controlled Trial of an Economic and Relationship-Strengthening Intervention to Reduce Alcohol Use in Malawi
With a full-scale randomized control trial, the investigators will evaluate the efficacy and cost effectiveness of Mlambe, an economic and relationship-strengthening intervention that provides incentivized saving accounts, financial literacy training, and relationship skills education to break the cycle of poverty around drinking, strengthen couple support and communication, and reduce heavy drinking among HIV-affected married couples with a partner who drinks alcohol in Malawi.
Inclusion: In a married or cohabitating union; Have at least one partner with a positive AUDIT-C screen in prior 3 months; Must also currently be on ART for at least 6 months; Must have disclosed their HIV status to their partner.
Exclusion: Severe intimate partner violence reported in previous 3 months and/or fear that safety would be at risk by participation in the study (reported at screening). Couples who participated in Mlambe's pilot study will also be excluded.