Testing two magnetic brain stimulation methods for sleep and fatigue in depression
Tests magnetic brain stimulation against sham in adults with depression or bipolar disorder.
Plain-language title generated from the registry record
Registry title: Effect of Intermittent and Continuous Theta Burst Stimulation on Sleep, Daytime Sleepiness, and Fatigue in Depression
Key facts
- Where
- Warsaw, PolandSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT06371352, who can take part
Where in Poland
- Institute of Psychiatry and NeurologyWarsaw, PolandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Jakub Antczak
- Trial code
- NCT06371352
- Record updated
- 15 October 2024
- Original description
Intermittent and continuous theta-burst stimulation (iTBS and cTBS respectively) are the newer modalities of transcranial magnetic stimulation with documented efficacy in treatment of depressed mood but with conflicting results regarding their efficacy in treatment of other symptoms of depression such as insomnia, daytime sleepiness and fatigue. This study will investigate the efficacy of iTBS over the left dorsolateral prefrontal cortex (DLPFC) and cTBS over the right DLPFC, compared to sham stimulation, in treatment of insomnia, daytime sleepiness and fatigue in depression.Read full original descriptionShow less
Effect of Intermittent and Continuous Theta Burst Stimulation on Sleep Quality, Sleep Propensity, Daytime Sleepiness, and Fatigue in Depression
Intermittent and continuous theta-burst stimulation (iTBS and cTBS respectively) are the newer modalities of transcranial magnetic stimulation with documented efficacy in treatment of depressed mood but with conflicting results regarding their efficacy in treatment of other symptoms of depression such as insomnia, daytime sleepiness and fatigue. This study will investigate the efficacy of iTBS over the left dorsolateral prefrontal cortex (DLPFC) and cTBS over the right DLPFC, compared to sham stimulation, in treatment of insomnia, daytime sleepiness and fatigue in depression.
Inclusion: severe or moderate depressive episode (according to international classification of diseases (ICD)-10) without psychotic symptoms at the time of inclusion; Diagnosis of major depression (F33.1 or F33.2) or bipolar disorder (F31.3 or F31.4); The score of the Athens Insomnia Scale five or more; Unchanged antidepressive pharmacotherapy at least one month prior to inclusion.
Exclusion: Suicidal ideations and/or attempts within three months prior to inclusion; Contraindications to transcranial magnetic stimulation, including ferromagnetic elements in head, pregnancy and epilepsy; Psychotic symptoms at the time of inclusion.