NCT06373289Recruiting
Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants
Target Oxygen Saturation Ranges in Infants With Bronchopulmonary Dysplasia Associated Pulmonary Hypertension
Source: ClinicalTrials.gov · Last updated 6 Oct 2026
Brief summary (registry, in English)
Around 50% of infants born extremely preterm develop a chronic lung disease known as bronchopulmonary dysplasia of which some infants will also develop pulmonary hypertension of which 50% of children will die before the age of 2. Physicians are currently limited in their ability to select the most appropriate oxygen targets that will improve outcomes in infants with this condition. This clinical trial will determine whether using different amounts of oxygen improve outcomes in infants with this disease.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 39 (estimated)
- First submitted
- 19 Mar 2024
- Start date
- 22 Sept 2026
- Primary completion date
- 6 Jul 2029
- Lead sponsor
- University of Alabama at Birmingham
- NCT number
- NCT06373289
What you commit to
- Study type: Interventional
- Planned participants: 39
- From 22 Sept 2026 to the primary completion date, 6 Jul 2029
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Major congenital anomalies
Who the study is looking for
- Between 22w 0/7d and 31w 6/7d gestation at birth
- Diagnosed with echocardiographic pulmonary hypertension (1) \>20% flow of blood across the PDA from the pulmonary to arterial circulation, (2) end-systolic flattening of the interventricular septum (eccentricity index \>1.3), or (3) right ventricular pressure estimates ≥ 35 mm Hg
- Receiving supplemental oxygen
- Have mature retinas
Age in the registry: 1 month to 5 months · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The University of Alabama at Birmingham Coordinator of this site? Confirm its status | Birmingham | United States | Recruiting |
| Yale New Haven Hospital Coordinator of this site? Confirm its status | New Haven | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.