Resistance Training and Nerve Signals in Multiple Sclerosis
Tests strength training effects on nerve signals and walking in adults with multiple sclerosis.
Plain-language title generated from the registry record
Registry title: Resistance Training and Corticospinal Excitability in Multiple Sclerosis
Key facts
- Where
- Aarhus and Copenhagen, DenmarkSee the 2 sites
Where in Denmark
- Department of Public HealthAarhus, DenmarkTaking people
- Department of Nutrition, Exercise and Sports, University of CopenhagenCopenhagen, DenmarkTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Aarhus
- Trial code
- NCT06374108
- Record updated
- 11 December 2024
- Original description
The goal of the present study is to investigate effects of progressive resistance training on central nervous system functioning (corticospinal excitability (CSE)) and walking capacity in persons with multiple sclerosis (pwMS). A total of 54 pwMS will be enrolled and randomized into 1 of 3 groups: high dose resistant training (RT), low dose RT, and waitlist control.Read full original descriptionShow less
Effects of Supervised Progressive Resistance Training on Central Nervous System Functioning (Corticospinal Excitability) and Walking Capacity in Persons With Multiple Sclerosis
The goal of the present study is to investigate effects of progressive resistance training on central nervous system functioning (corticospinal excitability (CSE)) and walking capacity in persons with multiple sclerosis (pwMS). A total of 54 pwMS will be enrolled and randomized into 1 of 3 groups: high dose resistant training (RT), low dose RT, and waitlist control.
Inclusion: Age ≥ 18 years; MS diagnosis according to the McDonald diagnostic criteria; Shows impairments in walking capacity; Ability to self transport to test and exercise.
Exclusion: Pacemaker or metallic implants; Hypertension (medically unregulated); Pregnancy; Neurological or other comorbidities that affects the nervous system; Relapse within the past 2 months; Participation in structured RT over the past 3 months (≥ 2 sessions/week).