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Poor Sleep During Pregnancy as Risk Factor for Post-partum Stress and Mental Health

Key facts

Where
Bologna and Rome, ItalySee the 2 sites

Where in Italy

  • Department of Biomedical and Neuromotor Sciences, Physiology campus, University of Bologna, Bologna, ItalyBologna, ItalyContact: Viviana Lo MartireTaking people
  • Department of Human Sciences, Guglielmo Marconi universityRome, ItalyContact: Chiara Baglioni, PhD, Associate ProfessorTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Trial details

Who runs it
University of Rome G. Marconi
Trial code
NCT06379074
Record updated
2 March 2026
Original description
Improving maternal mental health is a worldwide health priority. Nevertheless, several scientific sources highlighted lack of empirical data which could drive clinical practice. The present project addresses psychobiological mechanisms leading to peripartum mental disorders. It focuses on one key risk factor for psychopathology, which is poor sleep continuity. The project aims to describe the link between maternal poor sleep quality and the cascade of events which may enhance vulnerability to stress and risk for mental disorders and to evaluate the efficacy of an online automated psychological prenatal intervention directed to sleep problems in preventing these negative outcomes.Read full original descriptionShow less

Poor Sleep During Pregnancy as Risk Factor for Post-partum Stress and Mental Health: A Translational, Longitudinal and Clinical Study. Maternal Outcome After THERapy for Sleep (MOTHERS)

Improving maternal mental health is a worldwide health priority. Nevertheless, several scientific sources highlighted lack of empirical data which could drive clinical practice. The present project addresses psychobiological mechanisms leading to peripartum mental disorders. It focuses on one key risk factor for psychopathology, which is poor sleep continuity. The project aims to describe the link between maternal poor sleep quality and the cascade of events which may enhance vulnerability to stress and risk for mental disorders and to evaluate the efficacy of an online automated psychological prenatal intervention directed to sleep problems in preventing these negative outcomes.

Inclusion: age ≥ 18 yrs. old; good knowledge of Italian language; intention to continue pregnancy; BMI ranging 18-30 (i.e., without underweight or obesity following international criteria; WHO, 2013); ≤ 15th week of pregnancy at the time of recruitment.

Exclusion: assumption of illegal drugs; severe diagnosis of relevant somatic disorder; smoking; alcohol intake.

ClinicalTrials.gov NCT06379074