Taking people in MexicoPhase 4
Melatonin's Effect on Nighttime Blood Pressure and Sleep in OSA Patients (MEBP-OSA)
Key facts
- Who runs it
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
- Where
- Mexico City, MexicoSee the site
- Trial code
- Status
- Recruiting
- Phase
- Phase 4
- People taking part
- 50 people, planned
- Started
- 22 Jun 2023
- Expected to end
- 22 Jan 2028
- Type of study
- Interventional, 2 groups
- Treatments tested
- Melatonin 3 MG Oral Tablet
- Record updated
- 1 April 2026
Who can take part
- Age
- 18 years to 60 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 5 criteriaShow less
Who can take part
- Polisomnographic diagnosis of Obstructive Sleep Apnea
- Non-dipping blood pressure on Ambulatory blood pressure monitoring (ABPM):
Who cannot take part
- Use of sleep or psychiatric medication
- Neurologic or psychiatric disorder
- Use of Positive Airway Pressure (CPAP or Bipap)
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Where in Mexico
- National Institute of Medical Sciences and Nutrition Salvador Zubirán (INCMNSZ)Mexico City, MexicoContact: Matilde Valencia-Flores, PhDTaking people
About the trial
What the trial wants to find out
The goal of this clinical trial is to learn if melatonin works to treat comorbid insomnia in adults with OSA and nocturnal non-dipping blood pressure pattern.
Read full original descriptionShow less
The main question it aims to answer is:
Does melatonin maintain sleep during night and recover the dipping blood pressure pattern?
The 2 groups in the trial
- Usual care for nocturnal non-dipping Blood Pressurem in OSATreatment being tested
1\. Group of participants receives an intervention/treatment considered to be usual care
Treatment: Melatonin 3 MG Oral Tablet
- Oral administration of 3 mg/day of melatonin for 30 days in non-dipping Blood Pressure in OSATreatment being tested
2\. Group of participants receives oral Melatonin 3 mg/day during 30 days plus usual care
Treatment: Melatonin 3 MG Oral Tablet
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Impact of Melatonin Treatment on Blood Pressure Circadian Rhythm, Sleep and Metabolic Variables.
- Fit questions
- Built from NCT06380491, who can take part
- Record updated
- 1 April 2026