Postoperative Dexmedetomidine in Prevention of Postoperative Delirium
Key facts
- Who runs it
- Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.
- Where
- China1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 287 people enrolled
- Started
- 11 Nov 2023
- Ended
- 28 Apr 2024
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Dexmedetomidine injection
- Sufentanil injection
- Record updated
- 24 May 2024
Who can take part
- Age
- 65 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
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Who can take part
- elective surgery for lobectomy or segmentectomy
Who cannot take part
- local allergy to anesthetics
- patients with a clear preoperative history of nervous system and mental system diseases or long-term use of sedatives or antidepressants
- history of alcoholism, drug abuse or drug dependence
- have a history of brain surgery or injury
- epilepsy and associated mental and cognitive dysfunction, long-term stress stimulation, or psychological disorders
- sick sinus syndrome, second-degree or greater atrioventricular block or other contraindications for use of α2 adrenergic agonist
- liver and kidney insufficiency
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
The goal of this clinical trial is to learn how postoperative infusion of dexmedetomidine would influence postoperative delirium in elderly patients undergoing lung surgery. The main questions it aims to answer are :
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1. Does postoperative dexmedetomidine reduce the incidence of delirium after lung surgery? 2. Does postoperative dexmedetomidine introduce other medical problems? Researchers will compare dexmedetomidine and sufentanil to see if dexmedetomidine works to reduce delirium.
Participants will undergo routine postoperative care:
1. Patient-controlled self anesthesia with sufentanil only or combination of sufentanil and dexmedetomidine 2. Postoperative visit twice a day for at least seven days
The 2 groups in the trial
- ExperimentTreatment being tested
Treatment: Dexmedetomidine injection
- ControlExisting treatment, for comparison
Treatment: Sufentanil injection
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Postoperative Infusion of Dexmedetomidine for Prevention of Postoperative Delirium in Elderly Patients Undergoing Lung Surgery: A Randomized Controlled Trial
- Record updated
- 24 May 2024