NCT06384534Completed
Exercise Performance on Ambient Air vs. Low-Flow Oxygen Therapy in Pulmonary Vascular Disease (PVD)
Exercise Performance on Ambient Air vs. Commonly Prescribed Nasal Low Oxygen Therapy - a Non-inferiority Trial in Patients With Exercise Induced Desaturation Due to Pulmonary Vascular Disease (PVD)
Source: ClinicalTrials.gov · Last updated 10 Dec 2025
Brief summary (registry, in English)
The investigators aim to study the effect of SOT in Swiss residents with pulmonary vascular diseases (PVD) defined as pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 40 (actual)
- First submitted
- 17 Apr 2024
- Start date
- 1 Apr 2024
- Primary completion date
- 1 Jul 2025
- Lead sponsor
- University of Zurich
- NCT number
- NCT06384534
What you commit to
- Study type: Interventional
- Participants enrolled: 40
- From 1 Apr 2024 to the primary completion date, 1 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Severe hypoxemia needing supplemental oxygen therapy defined as partial pressure of O2 (PaO2) \< 6.9 Kilopascal (kPa)
Other illness
- Unability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc
Other
- Pregnancy
- Unability or contraindications to undergo the investigated intervention
Who the study is looking for
- Minimum 18 years of age
- Written informed consent
- Patients with diagnosed pulmonary arterial hypertension (PAH), distal chronic thromboembolic pulmonary hypertension (CTEPH)
- Former desaturation under exercise defined as Spo2-decrease \>3%
- Treated with a stable drug therapy (with no changes for at least 14 days prior to screening)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Zurich Coordinator of this site? Confirm its status | Zurich | Switzerland | Unknown status |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.