Studies how generalized epilepsy syndromes appear and progress over time
Observes people with idiopathic generalized epilepsy to describe symptoms, brain tests and long-term course.
Plain-language title generated from the registry record
Registry title: Idiopathic Generalized Epilepsy Syndromes
Key facts
- Where
- Hangzhou, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 4 and 40 years old?
Source: NCT06388174, who can take part
Where in China
- 2nd Affiliated Hospital, School of Medicine, Zhejiang University, ChinaHangzhou, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Shen Chun-Hong
- Trial code
- NCT06388174
- Record updated
- 27 August 2025
- Original description
The idiopathic generalized epilepsies (IGEs) have historically included the syndromes childhood absence epilepsy (CAE), juvenile absence epilepsy (JAE), juvenile myoclonic epilepsy (JME), and epilepsy with generalized tonic-clonic seizures alone (GTCA). Recognition of the IGEs is important for clinical care, as it informs diagnosis, prevents unnecessary investigation, allows optimal selection of anti-seizure medications (ASMs), and provides prognostic guidance.Read full original descriptionShow less
Idiopathic Generalized Epilepsy Syndromes: Clinical Features and Long-term Outcomes
The idiopathic generalized epilepsies (IGEs) have historically included the syndromes childhood absence epilepsy (CAE), juvenile absence epilepsy (JAE), juvenile myoclonic epilepsy (JME), and epilepsy with generalized tonic-clonic seizures alone (GTCA). Recognition of the IGEs is important for clinical care, as it informs diagnosis, prevents unnecessary investigation, allows optimal selection of anti-seizure medications (ASMs), and provides prognostic guidance.
According to the new ILAE definition in 2022, the study aims to describe the clinical features, electroencephalographic, imaging findings and long-term prognosis.
Inclusion: Patients are consecutively and prospectively enrolled from epilepsy center, with newly diagnosed epilepsy or established epilepsy; Patients have a diagnosis of idiopathic generalized epilepsy (IGE), according to the 2022 diagnostic criteria; Comprehensive clinical information is collected, and 24 hour video-electroencephalography is performed; Sign the informed consent forms.
Exclusion: Other epilepsy syndromes are considered during follow-up, such as genetic generalized epilepsy; Lost to follow-up.