NCT06389825Completed
Unravelling the Impact of Diet on Cardiovascular Health in Treated Heterozygous Familial Hypercholesterolemia.
Source: ClinicalTrials.gov · Last updated 21 Oct 2024
Brief summary (registry, in English)
The investigators will conduct a fully controlled dietary randomized crossover trial (RCT) including 10 adults with HeFH using lipid-lowering medication to investigate the impact of a diet low in red and processed meats and high in plant foods, reflecting Canada's Food Guide, in place of a standard North-American diet on LDL-cholesterol (LDL-C) levels and the plasma metabolome.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 11 (actual)
- First submitted
- 25 Apr 2024
- Start date
- 1 Apr 2024
- Primary completion date
- 30 Jun 2024
- Lead sponsor
- Laval University
- Diseases
- Familial hypercholesterolaemia
- NCT number
- NCT06389825
What you commit to
- Study type: Interventional
- Participants enrolled: 11
- From 1 Apr 2024 to the primary completion date, 30 Jun 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Personal history of cardiovascular disease
- Prevalent diabetes or anti-diabetic drug use
- Uncontrolled hypertension
- Allergies/aversions to components of the experimental diets
- Any other condition that would interfere with optimal participation in the intervention.
Age
- Age \>60 years
Other
- Homozygous FH
- Severe obesity
- Unstable body weight for \>3 months
- Genetic hypertriglyceridemia
Who the study is looking for
- Genetically-defined HeFH
- Premenopausal women with a regular menstrual cycle for \>3 months
- Postmenopausal women (without hormone replacement)
Age in the registry: 18 years to 60 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| INAF-NUTRISS Université Laval Coordinator of this site? Confirm its status | Québec | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.