Inflammatory Resolution in Cardiometabolic Health and Disease
Key facts
- Where
- Aarhus, DenmarkSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT06390189, who can take part
Where in Denmark
- Steno Diabetes Center Aarhus, Aarhus University HospitalAarhus, DenmarkTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Aarhus
- Trial code
- NCT06390189
- Record updated
- 28 June 2024
- Original description
The specific aim of this study is to determine molecular pathways that differentiate metabolically healthy vs unhealthy human phenotypes, and to investigate the therapeutic potential of pro-resolving lipids. Investigators will recruit volunteers that are metabolically healthy or unhealthy that fall within three BMI ranges: lean (18.-24.9 kg/m2), overweight (25.0-29.9 kg/m2) and obese (>30.0 kg/m2). Investigators hypothesize that metabolically healthy individuals have a superior endogenous capacity to regulate an inflammatory/resolving response.Read full original descriptionShow less
Inflammatory Resolution in Cardiometabolic Health and Disease - an Aarhus Based Cohort
The specific aim of this study is to determine molecular pathways that differentiate metabolically healthy vs unhealthy human phenotypes, and to investigate the therapeutic potential of pro-resolving lipids. Investigators will recruit volunteers that are metabolically healthy or unhealthy that fall within three BMI ranges: lean (18.-24.9 kg/m2), overweight (25.0-29.9 kg/m2) and obese (>30.0 kg/m2). Investigators hypothesize that metabolically healthy individuals have a superior endogenous capacity to regulate an inflammatory/resolving response.
Inclusion: Informed signed consent has been obtained from the volunteer; The volunteer has a BMI greater than 18.5 kg/m2; Men and women over the age of 18 are included.
Exclusion: An MD determines that the individual is on too many medications to participate; The individual takes a medication that is approved by the MD, but he/she is not willing or not able to wait with any potential morning medication until after their fasted blood-draw; The individual regularly uses medication that affects inflammatory resolution (e.g., low-dose aspirin); The individual uses immunosuppressive drugs (e.g., methotrexate); The individual has been drinking alcohol two days before the study visit; The individual states that they have increased bleeding tendency or are using anti-coagulant (blood thinning) medication; The study staff contacting a potential participant perceives that the individual has difficulty understanding the information; The individual has some form of chronic inflammation; The individual regularly consumes fish oils (omega 3); The individual has significant gastrointestinal problems; The individual smokes or uses chewing tobacco; The individual has tattoos or body piercings on the forearms and / or the stomach that can affect the examination; The individual does not follow instructions given in the research study.