Early Testing and Treatment for Hidden Asthma or COPD in Adults
Tests early diagnosis and treatment in adults with undiagnosed asthma or COPD.
Plain-language title generated from the registry record
Registry title: Early Diagnosis and Treatment of Undiagnosed Asthma or COPD: THE UCAP 2 TRIAL
Key facts
- Where
- Hamilton, Kingston, Ottawa, Québec, Saskatoon, and Toronto, CanadaSee the 6 sites
Where in Canada
- St. Joseph's Hamilton HealthcareHamilton, CanadaTaking people
- Kingston Health Sciences Centre, Queen's UniversityKingston, CanadaTaking people
- Ottawa Hospital - General CampusOttawa, CanadaTaking people
- Institut universitaire de cardiologie et de pneumologie de QuébecQuébec, CanadaTaking people
- Royal University HospitalSaskatoon, CanadaTaking people
- St. Michael's Hospital, Unity Health TorontoToronto, CanadaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Ottawa Hospital Research Institute
- Trial code
- NCT06392776
- Record updated
- 23 September 2026
- Original description
Our research group has found that Canadians with undiagnosed asthma or chronic obstructive pulmonary disease (COPD) have increased respiratory symptoms and worse health-related quality of life.Read full original descriptionShow less
Early Diagnosis and Treatment of Undiagnosed Asthma or COPD: THE UCAP 2 TRIAL
Our research group has found that Canadians with undiagnosed asthma or chronic obstructive pulmonary disease (COPD) have increased respiratory symptoms and worse health-related quality of life.
The investigators recently developed and validated an on-line questionnaire to accurately identify these symptomatic, undiagnosed individuals.
The investigators will advertise in the community asking individuals to complete the on-line questionnaire at home, at their leisure, to determine if they are at risk of asthma or COPD. Those at risk will be invited to participate in a randomized, controlled clinical trial to determine whether early diagnosis of previously undiagnosed asthma or COPD and subsequent treatment by the primary care practitioner will improve their quality of life.
Inclusion: Individuals at least 18 years old; Individuals must be symptomatic with respiratory symptoms; Individuals must complete the UCAP-Q questionnaire and score a ≥ 6% probability of having either asthma or COPD; Individuals who have given written informed consent to participate in this trial in accordance with local regulations; Individual must be able to perform pre and post bronchodilator spirometry to measure lung function; Additional Inclusion Criteria for the Randomized Controlled Trial (RCT):; Individuals who have undiagnosed airflow obstruction on spirometry testing (i.e. Asthma or COPD) will be asked to participate in the RCT.
Exclusion: Individuals who report a previous diagnosis of asthma, COPD, history of lung cancer, bronchiectasis, interstitial lung disease, cystic fibrosis or other significant diagnosed lung disease; Individuals currently using inhaled corticosteroids or long-acting bronchodilators; Individuals with history of myocardial infarction, stroke, aortic or cerebral aneurysm, or detached retina or eye surgery within the past 3 months (spirometry is contraindicated); Individuals currently under the care of a Respirologist; Individuals who are in the third trimester of pregnancy; Individuals involved in another interventional trial.