Home-based support program for stroke survivors facing social hardship
Tests a home-based support team in adults aged 18 to 75 after stroke.
Plain-language title generated from the registry record
Registry title: SDOH-Homecare Intervention Focus Team (SHIFT) Trial to Improve Stroke Outcomes
Key facts
- Where
- New York, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT06397937, who can take part
Where in United States
- Columbia University Medical CenterNew York, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Columbia University
- Trial code
- NCT06397937
- Record updated
- 8 April 2026
- Original description
Primary Goal:Read full original descriptionShow less
The SDOH-Homecare Intervention Focus Team (SHIFT) Trial to Mitigate Social Determinants of Stroke Outcomes and Build Community Capacity (The SHIFT Trial)
Primary Goal:
To test the hypothesis that among stroke patients 18-75 years with ≥3 SDOH risk factors, SHIFT will improve: (1) functional outcomes as measured by the SIS (Primary Outcome), (2) physiological outcomes as measured by changes in blood pressure and cognition, (secondary outcomes) and (3) epigenetic allostatic load biomarkers (exploratory outcome) such as DNA methylation (DNAm) and telomere length, at 6 months and 1-year post-stroke, compared with usual care (UC).
Inclusion: Ischemic stroke (arterial subtypes) or primary intracerebral hemorrhage (excluding diagnosis of probable cerebral amyloid angiopathy by Boston Criteria); African American/Black or Hispanic race-ethnicity; Age 18-75 years old; Have at least 3 SDOH barriers from within the 5 SDOH domains (Social and Community, Education, Economic, neighborhood/environment, Health Care); Have a discharge plan to 1) home with or without home services, or 2) acute rehabilitation with plan to return home after; Pre-stroke Modified Rankin Scale score of ≤3; Residence in New York City; English or Spanish speaking; Can provide informed consent and engage in the initial assessment prior to stroke discharge; Lives in a household with a telephone, and has a caregiver (family member or Home Health Aide) if not fully independent on discharge. If the patient requires a family member to assist with activities of daily living or decision-making, the family member must state a willingness to be present at home visits where their assistance is needed.
Exclusion: Diagnosis of dementia or other neurological diagnosis that affects cognition; Subarachnoid hemorrhage; Discharge disposition to a long-term care facility; Diagnosis of active major depression; Aphasia severe enough to preclude initial examination; Impaired level of consciousness at initial cognitive assessment; Diagnosis of probable cerebral amyloid angiopathy by Boston criteria; Life expectancy less than 1 year.