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Gait Training in Changing Environments to Improve Walking Balance After Stroke

Tests high-intensity walking training in changing settings for adults with long-term stroke.

Plain-language title generated from the registry record
Registry title: Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke

Key facts

Where
Chicago and Hines, United StatesSee the 2 sites

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 80 years old?

Source: NCT06400186, who can take part

Where in United States

  • Northwestern UniversityChicago, United StatesNot yet recruiting
  • Edward Hines Jr. VA Hospital, Hines, ILHines, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
VA Office of Research and Development
Trial code
NCT06400186
Record updated
14 August 2026
Original description
Stroke is a leading cause of disability in the United States, affecting approximately 795,000 people annually. The Veteran's Health Administration provides over 60,000 outpatient visits for stroke-related care annually at a cost of over $250 million. Among ambulatory people with chronic stroke (PwCS), impaired balance is a common health concern that substantially limits mobility (those with the worst balance walk the least). This project will explore adaptive strategies employed by PwCS in balance challenging environments and if a novel gait training intervention using a robotic device to amplify a person's self-generated movements can improve walking balance. The development of effective interventions to increase walking balance among PwCS will positively impact Veterans' health, quality of life, and ability to participate in walking activities.Read full original descriptionShow less

Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke

Stroke is a leading cause of disability in the United States, affecting approximately 795,000 people annually. The Veteran's Health Administration provides over 60,000 outpatient visits for stroke-related care annually at a cost of over $250 million. Among ambulatory people with chronic stroke (PwCS), impaired balance is a common health concern that substantially limits mobility (those with the worst balance walk the least). This project will explore adaptive strategies employed by PwCS in balance challenging environments and if a novel gait training intervention using a robotic device to amplify a person's self-generated movements can improve walking balance. The development of effective interventions to increase walking balance among PwCS will positively impact Veterans' health, quality of life, and ability to participate in walking activities.

Inclusion: History of chronic stroke (more than 6 months post-stroke) with weakness on one side; Ability to ambulate over ground for 10 meters with or without a single cane, and/or ankle-foot orthosis; Ability to tolerate 10 minutes of standing.

Exclusion: Concomitant central or peripheral neurological injury (i.e. traumatic head injury or peripheral nerve damage in lower limbs) affecting gait and balance; Enrollment in concurrent physical therapy or research involving gait or balance training; Presence of cognitive impairment (score of 22/30 on the Montreal Cognitive Assessment scale (MoCA)); Severe cardiovascular and pulmonary disease affecting gait and balance; History of recurrent fractures or known orthopedic problems in the lower extremities (i.e. heterotopic ossification) affecting gait and balance; Presence of aphasia (score of 71/100 on the Mississippi Aphasia Screening Test (MAST)); Excessive spasticity in lower limbs (score of > 3 on the Modified Ashworth Scale; Evidence of cerebellar ataxia; Presence of unhealed decubiti or other skin compromise; Use of braces/orthotics crossing the knee joint; Known pregnancy.

ClinicalTrials.gov NCT06400186