Use of CPETarm for Risk Stratification of Patients With CLTI

Who can take part

• Ability and willingness to give written informed consent
• Diagnosis of chronic limb threatening ischaemia, undergoing one of the following procedures: Infra inguinal bypass, Extra anatomical bypass, Common femoral endarterectomy, Endovascular treatment, Primary amputation

Who cannot take part

• Active arrthymic requiring the initiation or up titration of an anti arrthymic medication
• Patients with active medical conditions deemed an absolute contraindication for undertaking CPET
• Ongoing evaluation for coronary artery disease (e.g awaiting stress test or cardiac catheterisation or requiring the up titration of anti anginal medications)
• Active congestive cardiac failure requiring the initiation or up titration of diuretic therapy
• Severe cardiac valvular stenosis
• Psychiatric disorder or dementia precluding them from consenting for research and/or undertaking testing and/or follow up
• Physical disability precluding ability to perform CPETarm