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Studying how stroke affects sentence-building speech in aphasia

Studies how stroke-related aphasia affects building sentences in adults 18 and older.

Plain-language title generated from the registry record
Registry title: Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia

Key facts

Where
College Park, United StatesSee the site

Where in United States

  • University of MarylandCollege Park, United StatesTaking people

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Trial details

Who runs it
University of Maryland, College Park
Trial code
NCT06405594
Record updated
3 September 2024
Original description
The proposed research is relevant to public health because stroke is a leading cause of long-term disability among older adults and communication impairments resulting from stroke have a significant negative impact on quality of life. By seeking to better understand post-stroke aphasia, this project lays the groundwork for development of new interventions, and aligns with NIDCD's priority areas 1 (understanding normal function), 2 (understanding diseases), and 3 (improving diagnosis, treatment, and prevention).Read full original descriptionShow less

Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia

The proposed research is relevant to public health because stroke is a leading cause of long-term disability among older adults and communication impairments resulting from stroke have a significant negative impact on quality of life. By seeking to better understand post-stroke aphasia, this project lays the groundwork for development of new interventions, and aligns with NIDCD's priority areas 1 (understanding normal function), 2 (understanding diseases), and 3 (improving diagnosis, treatment, and prevention).

Inclusion: At least 18 years of age; Persons with acquired aphasia are defined as those with a language impairment following left hemisphere brain injury (most likely a stroke); Neurotypical adults need to be either young (ages 18-30 years) or older (> 60 years); Native (or primary) speakers of English.

Exclusion: Prior neurological or psychiatric diagnoses or developmental disabilities before the onset of aphasia; do not speak English fluently.

ClinicalTrials.gov NCT06405594