Studying Heart Pouch Tissue and Blood Clots in Atrial Fibrillation Patients
Studies heart pouch tissue and blood from adults with atrial fibrillation during appendage closure surgery.
Plain-language title generated from the registry record
Registry title: Left Atrial Appendage Arrhythmogenic and Thrombogenic Substrate
Key facts
- Where
- Copenhagen, DenmarkSee the site
Where in Denmark
- RigshospitaletCopenhagen, DenmarkTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital Bispebjerg and Frederiksberg
- Trial code
- NCT06405750
- Record updated
- 15 January 2026
- Original description
The purpose of the project is to elucidate whether it is possible to identify which patients are at risk of forming blood clots that can cause stroke based on analysis of the electrocardiogram.Read full original descriptionShow less
Left Atrial Appendage Arrhythmogenic and Thrombogenic Substrate
The purpose of the project is to elucidate whether it is possible to identify which patients are at risk of forming blood clots that can cause stroke based on analysis of the electrocardiogram.
In connection with the operation, the small pouch known as the auricle of the heart is closed, which can be completely removed after closing. This procedure is common in patients with atrial fibrillation to protect the brain from stroke. In the project, all patients will have this auricle closed if they agree to participate in the project.
After closure, the auricle is usually discarded. We will analyze the blood and the auricle tissue taken (if available) in connection with the operation itself, together with the analysis of the electrocardiogram recorded before the planned heart operation.
Inclusion: signed informed consent AND; planned any open-heart surgery:; CABG; valve repair or replacement; aorta surgery; any combination of the above.
Exclusion: current endocarditis; follow-up not possible.