Tests platelet-rich fibrin in tooth extraction sockets before head and neck radiation
Tests platelet-rich fibrin for healing tooth sockets in adults with head and neck cancer.
Plain-language title generated from the registry record
Registry title: Topical Application of PRF Before Radiation Therapy
Key facts
- Where
- Giessen, GermanySee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with head and neck cancer who will have radiation therapy and need teeth removed on both sides of the mouth. It compares PRF in the tooth socket with natural healing.
- Age
- From 18 Years to 99 Years
- Sex
- All sexes can join
- Disease stage
- Head and neck cancer with radiation therapy planned.
- Earlier treatment
- No earlier radiation therapy in the head and neck area. No earlier or current treatment with bisphosphonates or equivalent modern biologics.
Main reasons for not taking part
- Earlier radiation therapy in the head and neck area
- Earlier or current treatment with bisphosphonates or equivalent modern biologics
- Pregnancy or breastfeeding
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 99 years old?
Source: NCT06406530, who can take part
Where in Germany
- University of GiessenGiessen, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Giessen
- Trial code
- NCT06406530
- Record updated
- 11 April 2025
- Original description
The primary goal of this study is to observe whether PRP promotes the wound healing before a radiation therapy or not, compared to the natural healing of a tooth extraction socket.Read full original descriptionShow less
Topical Application of PRF in Tooth Extraction Sockets Before Radiation Therapy for Head and Neck Cancer
The primary goal of this study is to observe whether PRP promotes the wound healing before a radiation therapy or not, compared to the natural healing of a tooth extraction socket.
Secondary aim is to monitore the effect on the pain perception.
Inclusion: Head and neck cancer with planed radiation therapy; Bilateral tooth extraction; Similar tooth size; Atraumatic tooth extractions without flap surgery; Patients age above 18y of age.
Exclusion: Prior radiation therapy in the head and neck area; Prior and current therapy with bisphosphonates or equivalent modern biologics; Patients during pregnancy or breastfeeding.