Why Some People With Endometriosis Do Not Respond to Hormone Medicine
Studies why endometriosis does not respond to hormone treatment, in adults.
Plain-language title generated from the registry record
Registry title: Risk Factors for Non-response to Hormonal Medical Therapy in Patients With Endometriosis
Key facts
- Where
- Bologna, ItalySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 50 years old?
Source: NCT06413381, who can take part
Where in Italy
- IRCCS Azienda Ospedaliero-Universitaria, Policlinico Sant'OrsolaBologna, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Trial code
- NCT06413381
- Record updated
- 1 August 2024
- Original description
Determine the proportion of patients with endometriosis unresponsive to medical therapy and to compare the clinical and ultrasonographic characteristics of this group of patients (study group) with the clinical and ultrasonographic characteristics of patients responsive to medical therapy (control group).Read full original descriptionShow less
Risk Factors for Non-response to Hormonal Medical Therapy in Patients With Endometriosis
Determine the proportion of patients with endometriosis unresponsive to medical therapy and to compare the clinical and ultrasonographic characteristics of this group of patients (study group) with the clinical and ultrasonographic characteristics of patients responsive to medical therapy (control group).
Inclusion: age between 18 and 50 years; patients with endometriosis-related pain symptoms (dyspareunia, dyschezia, dysmenorrhea, chronic pelvic pain, dysuria, periovulatory pain, with at least one of these symptoms presenting Numerical Pain Rating Scale intensity > 5); indication for administration of oral hormonal medical treatment for endometriosis; acquisition of informed consent.
Exclusion: current or previous pelvic infections; previous pelvic surgery (hysterectomy, salpingectomy, ovarian cyst removal, myomectomy, surgery for endometriosis, bowel resections); history of malignancy or current suspicion of gynecologic malignant lesions; positive history of other causes of chronic pelvic pain; patients with contraindications to oral hormone treatment; post-menopausal status.