NCT06414967Recruiting
Study to Evaluate Music Therapy on Irritability and Impulsivity in Patients With Huntington's Disease (MUSIC-HD)
Pilot Study Evaluating the Benefits of Music Therapy Combined With Conventional Treatment on Irritability and Impulsivity in Patients With Huntington's Disease (MUSIC-HD)
Source: ClinicalTrials.gov · Last updated 29 Dec 2025
Brief summary (registry, in English)
The study is an open-label clinical trial evaluating whether music therapy combined with conventional management reduces irritability and impulsivity in 15 patients with early-stage Huntington's disease. This pilot study aims to show the interest of alternative non-pharmacological measures such as a digital music therapy tool, adapted to an audience of Huntington's patients, to help manage the psychobehavioral symptoms frequently observed in this affection, and to avoid breakdowns due to caregiver exhaustion.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 15 (estimated)
- First submitted
- 10 May 2024
- Start date
- 15 Oct 2024
- Primary completion date
- Jul 2026
- Lead sponsor
- Poitiers University Hospital
- Diseases
- Huntington's disease
- NCT number
- NCT06414967
What you commit to
- Study type: Interventional
- Planned participants: 15
- From 15 Oct 2024 to the primary completion date, Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Significant hearing impairment
Other
- Inability to give free and informed consent for study participation
- Participating to another study the day of enrollement
- Persons benefiting from enhanced protection, i.e.persons deprived of their liberty by a judicial or administrative decision, adults under legal and finally patients in a vital emergency situation.
Who the study is looking for
- Age \>= 18 years
- Huntington disease genetically confirmed by the presence of at least 35 repeats of the CAG triplet in exon 1 of the HTT gene
- UHDRS (Unified Huntington's disease Rating Scale) score \<= 5 with a diagnostic confidence score =4
- Absence of significant cognitive impairment MoCA \>=24
- Stable drug therapy in the 28 days prior inclusion and during the study
- Without legal tutors or subordination
- Affiliated to a health insurance system as required by the French law on biomedical research
- Written informed consent for participation in the study
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU Poitiers / CIC Coordinator of this site? Confirm its status | Poitiers | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.