Genes and How Kidney Disease Gets Worse Over Time
Studies whether genetic differences influence kidney disease development and progression in adults.
Key facts
- Who runs it
- Ospedale San Raffaele
- Where
- Milan, ItalySee the site
- Trial code
- Registry title
- Genetics in the Progression of Nephropathies
- Status
- Recruiting
- People taking part
- 10,000 people, planned
- Started
- 19 May 2006
- Expected to end
- 19 May 2041
- Type of study
- Observational
- Treatments tested
- genetic polymorphisms
- Record updated
- 16 May 2024
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with a specific kidney disease. It studies how genes affect the start and worsening of kidney diseases.
- Age
- 18 years and older
- Sex
- All sexes can join.
- Disease stage
- A specific kidney disease must be present. The record does not give a stage or severity.
Main reasons for not taking part
- The record says exclusions are set in the different sub-protocols.
The registry criteria, word for word
Show all 2 criteriaShow less
Who can take part
- . presence of specific renal disease
Who cannot take part
- to be evaluated in the different sub-protocols
Where in Italy
- IRCCS Ospedale San RaffaeleMilan, ItalyContact: Chiara Lanzani, MDTaking people
About the trial
What the trial wants to find out
This study evaluates the role of genetic in the development and progression of different nephropaties with particular attention to:
Read full original descriptionShow less
* AKI * CKD * Hypertension * ADPKD * CKD-MBD * Patients with decompensated heart failure undergoing either medical or surgery therapy * Patients with hematologic cancer exposed to chemotherapeutic agents or undergoing allogeneic bone marrow transplantation * glomerular diseases
The group in the trial
- Patients with acute or chronic nephropathy
1. Patients with chronic nephropathies 2. Patients with acute nephropathy 3. Patients with nephrectomy 4. Candidate Patients to major surgery 5. Patients with decompensated heart failure undergoing either medical or surgical therapy 6. Acute critically ill patients (e.g sepsis, post-operative) 7. Patients with hypertension 8. Patients with hematologic cancer exposed to chemotherapeutic agents or undergoing allogeneic bone marrow transplantation. 9. Long-term surviving patients who received bone marrow transplantation.
Treatment: genetic polymorphisms
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- The Genetic Contribution to Progression of Kidney Disease
- Plain-language title
- Genes and How Kidney Disease Gets Worse Over TimeGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 16 May 2024