Calcium in brain arteries and outcomes after clot removal for stroke
Studies whether calcium in brain arteries affects results of clot removal in adults with stroke.
Plain-language title generated from the registry record
Registry title: The Correlation of Intracranial Artery Calcification and Outcomes of Mechanical Thrombectomy
Key facts
- Where
- Guangzhou, ChinaSee the site
Where in China
- Zhujiang Hospital, Southern Medical UniversityGuangzhou, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Zhujiang Hospital
- Trial code
- NCT06418698
- Record updated
- 28 July 2025
- Original description
CAIS-MT is a single-center, prospective cohort study, to evaluate the correlation between outcomes of endovascular treatment(EVT) and intracranial artery calcification(IAC) in patients with acute ischemic stroke due to large or medium vessel occlusion.Read full original descriptionShow less
The Prediction of Intracranial Artery Calcification on Adverse Outcomes of Large Vessel Occlusive, Acute Ischemic Stroke Patients After Mechanical Thrombectomy: A Prospective Cohort, Observational Study
CAIS-MT is a single-center, prospective cohort study, to evaluate the correlation between outcomes of endovascular treatment(EVT) and intracranial artery calcification(IAC) in patients with acute ischemic stroke due to large or medium vessel occlusion.
Inclusion: Male or non-pregnant women with acute stroke symptoms aged over 18 years; Occlusion of the intracranial internal carotid artery, the middle cerebral artery, the anterior cerebral artery, the posterior cerebral artery, basilar artery and intracranial vertebral artery confirmed by CT, MR angiography, or digital subtraction angiography; No absolute contraindication to iodinated contrast media; Planned treatment with EVT by clinical care team; Informed consent obtained from patients or their legal representatives; Willing to be followed up as required by the clinical study protocol.
Exclusion: Previous cerebrovascular intervention treatment or craniotomy; Acute ischemic stroke occurs over 24 hours of time last known well; Neurologic deficits caused by diagnoses other than ischemic stroke, such as intracerebral hemorrhage, subarachnoid hemorrhage, or intracranial tumors; With other underlying factors leading to IAC, such as hyperthyroidism, end-stage renal disease, long-term oral intake of vitamin K antagonist(Warfarin), chronic vitamin D deficiency or overdose, persistent hypomagnesemia, persistent hypercalcemia, persistent hyperphosphatemia and high oral calcium intake; Severe renal insufficiency (estimated glomerular filtration rate < 30ml/min or serum creatinine > 220μmol/L (2.5mg/dl)); Lack of non-contract CT images on admission and significant artifacts in CT images preventing IAC measurement.