Testing a breathing measurement to monitor asthma in adults
Checks whether an oscillometry breathing test adds value to asthma monitoring in adults.
Key facts
- Who runs it
- Universitair Ziekenhuis Brussel
- Where
- Brussels, BelgiumSee the site
- Trial code
- Registry title
- The Potential Added Value of Impulse Oscillometry in Asthma Monitoring
- Status
- Recruiting
- People taking part
- 50 people, planned
- Started
- 1 Sept 2024
- Planned end
- Apr 2026
- Type of study
- Interventional
- Treatments tested
- Full lung function
- Multiple breath nitrogen washout
- Impulse oscillometry
- Record updated
- 15 September 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with asthma whose doctor has decided to raise or lower their asthma medicine. It studies whether a breathing test called impulse oscillometry helps in following asthma.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- Adults with asthma who are prescribed a step-up or step-down of their asthma treatment at an outpatient hospital visit
Main reasons for not taking part
- Unstable asthma
- Needing oral corticosteroids in the 4 weeks before joining
- Needing a course of (respiratory) antibiotics in the 4 weeks before joining
- Any major medical issue in the 4 weeks before joining
The registry criteria, word for word
Show all 2 criteriaShow less
Who can take part
- Adult asthma patients with a scheduled consultation at the outpatient hospital to whom a step-up or step-down of their pharmacological asthma treatment is prescribed
Who cannot take part
- Unstable asthma (defined as need for oral corticosteroids or (respiratory) antibiotic course in the 4 weeks before inclusion or any major medical issue in the 4 weeks before inclusion)
Where in Belgium
- Universitair Ziekenhuis BrusselBrussels, BelgiumContact: Shane Hanon, Prof. Dr. MD.Taking people
About the trial
What the trial wants to find out
The goal of this longitudinal observational study is to learn if impulse oscillometry (IOS) has an added value in asthma monitoring in adult asthma patients who are prescribed a change in asthma maintenance therapy. The main questions it aims to answer are:
Read full original descriptionShow less
* Is there a difference in the change in IOS parameters and FEV1 respectively, stratified according to change in asthma control test? * Is there a difference in the change in IOS parameters and FEV1 respectively, stratified according to change in other questionnaire such as the asthma control questionnaire and the asthma quality of life questionnaire. * Are the proposed minimal clinically important differences (MCIDs) valid for short follow-up periods (3 - 6 months)?
Participants will undergo lung function testing (full lung function, multiple breath nitrogen washout, impulse oscillometry) and questionnaires (asthma control test, asthma control questionnaire, asthma quality of life questionnaire), once during the baseline visit and once during the follow-up visit three to six months later.
The group in the trial
- Adult asthma patientsTreatment being tested
Lung function tests (full lung function, multiple breath nitrogen washout, impulse oscillometry) and questionaires (asthma control test, asthma control questionnaire, asthma quality of life questionnaire) will be conducted, once at baseline and once 3 - 6 months later during follow-up.
Treatment: Full lung function, Multiple breath nitrogen washout, and Impulse oscillometry
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- The Potential Added Value of Impulse Oscillometry in Asthma Monitoring
- Plain-language title
- Testing a breathing measurement to monitor asthma in adultsGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 15 September 2025