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Checking how common heart amyloidosis is in very old heart failure patients

Studies how often heart amyloidosis occurs in people aged 80 or older with heart failure.

Key facts

Who runs it
Gérond'if
Where
Amiens, Angers, Bordeaux, Boulogne-Billancourt, Carcassonne, Castres, Chambray-lès-Tours, Dijon, Grenoble, Issy-les-Moulineaux, Ivry-sur-Seine, Lille, Limeil-Brévannes, Limoges, Lyon, Marseille, Melun, Montpellier, Nancy, Nantes, Nice, Orléans, Paris, Poitiers, Rennes, Rouen, Toulouse, Tours, Trélazé, and Villeurbanne, FranceSee the 36 sites
Trial code
Registry title
Cardiac Amyloidosis pRevaleNce of in OLDer Subjects Affected by Heart Failure
Status
Recruiting
People taking part
637 people, planned
Started
1 Jul 2024
Expected to end
2 Feb 2028
Type of study
Observational
Record updated
20 April 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for people aged 80 or older who were in hospital for heart failure in the last 12 months. Their heart muscle wall must be thickened on an ultrasound scan of the heart.

Age
80 years or older
Sex
All sexes can join
Disease stage
Hospitalised for worsening heart failure in the last 12 months, with a thickened heart wall (septum or left ventricle) of 12 mm or more on heart ultrasound (echocardiography)

Main reasons for not taking part

  • Refusing to take part
  • In a palliative care unit
  • Under guardianship
  • Already has a definite diagnosis of cardiac amyloidosis
  • Cannot have a bone scintigraphy scan

The registry criteria, word for word

Show all 9 criteriaShow less

Who can take part

  • Aged ≥ 80 years
  • Hospitalised for decompensation of heart failure in the last 12 months
  • Subjects with hypertrophy of the septum or left ventricle at cardiac echography (defined as ≥ 12 mm)
  • Subjects able to undergo a bone scintigraphy scan
  • Subjects willing to participate

Who cannot take part

  • Subjects with a definite diagnosis of cardiac amyloidosis
  • Subjects refusing to participate
  • Subjects admitted to palliative care unit
  • Subjects under guardianship

Where in France

  • Chu Amiens PicardieAmiens, FranceContact: Nysrine BENNOUNA, MDTaking people
  • CHU AngersAngers, FranceContact: Cédric NNWEILER, MD, PHDTaking people
  • CHU BordeauxBordeaux, FranceContact: Isabelle BOURDEL-MARCHASSON, MD, PHDTaking people
  • Ambroise Paré HospitalBoulogne-Billancourt, FranceContact: Marion PEPIN, MDTaking people
  • Centre Hospitalier de CarcassonneCarcassonne, FranceContact: Hanna BAKANOVA, DrTaking people
  • Centre Hospitalier Intercommunal de Castres MazametCastres, FranceContact: Soumiya MENHOUR, MDTaking people
  • CHU Trousseau-ToursChambray-lès-Tours, FranceContact: Laurent FAUCHIER, MD, PHDTaking people
  • CHU DijonDijon, FranceContact: Jérémie VOVELLE, MDTaking people
  • CHU Grenoble AlpesGrenoble, FranceContact: Laure ALLAN-PATTOGLIA, MDTaking people
  • Corentin Celton HospitalIssy-les-Moulineaux, FranceContact: Anthony MEZIERE, MDNot yet recruiting
  • Charles Foix HospitalIvry-sur-Seine, FranceContact: Joël BELMIN, MD, PHDTaking people
  • CHU LilleLille, FranceContact: François PUISIEUX, MD, PHDTaking people
  • Emile Roux HospitalLimeil-Brévannes, FranceContact: Amaury BROUSSIER, MDTaking people
  • CHU LimogesLimoges, FranceContact: Achille TCHALLA, MDTaking people
  • Chu LyonLyon, FranceContact: Michel CHUZEVILLE, MDTaking people
  • CHU MarseilleMarseille, FranceContact: Anne-Laure COUDERC, MD, PHDTaking people
  • GH Sud Ile-de-FranceMelun, FranceContact: Cyrus MOÏNI, MDTaking people
  • CHU MontpellierMontpellier, FranceContact: Hubert BLAIN, MD, PHDTaking people
  • Clinique du Millénaire-MontpellierMontpellier, FranceContact: Philippe GALLET DE SANTERRE, DrTaking people
  • CHRU NancyNancy, FranceContact: Laure JOLY, MDTaking people
  • CHU NantesNantes, FranceContact: Anne Sophie BOUREAU, MDTaking people
  • CHU NiceNice, FranceContact: Olivier GUERIN, MD, PHDTaking people
  • Hôpital Privé Gériatrique LES SOURCES-NiceNice, FranceContact: Anne-Marie BARISIC, MDTaking people
  • CHU OrléansOrléans, FranceContact: Matthieu COULONGEAT, MDTaking people
  • Bretonneau HospitalParis, FranceContact: Virginie FOSSEY-DIAZ, MDTaking people
  • Europeen Georges Pompidou HospitalParis, FranceContact: Elena PAILLAUD, MD, PHDTaking people
  • Geriatric Department, Broca HospitalParis, FranceContact: Olivier Hanon, MD PhDTaking people
  • Lariboisière HospitalParis, FranceContact: Matthieu LILAMAND, MDTaking people
  • Saint Joseph HospitalParis, FranceContact: Yara ANTAKLY HANON, MDTaking people
  • CHU PoitiersPoitiers, FranceContact: Marc PACCALIN, MD, PHDTaking people
  • CHU RennesRennes, FranceContact: Dominique SOMME, MD, PHDTaking people
  • CHU Rouen, Charles Nicole hospitalRouen, FranceContact: Frédéric ROCA, MDTaking people
  • CHU ToulouseToulouse, FranceContact: Olivier TOULZA, MDTaking people
  • CHRU Tours-Bretonneau HospitalTours, FranceContact: Bertrand FOUGERE, MD, PHDTaking people
  • Clinique Saint Joseph TrelazeTrélazé, FranceContact: Laureen LABORY, MDTaking people
  • Médipôle Hôpital Mutualiste VilleurbanneVilleurbanne, FranceContact: Antoine JOBBE-DUVAL, MDTaking people

About the trial

What the trial wants to find out

Tne aim purpose of this observational, multicentre and propective study is to determine the prevalence of cardiac amyloidosis in geriatric patients aged 80 years and older hospitalized within the last 12 months for heart failure with left ventricular hypertrophy (septum ≥ 12 mm) on echocardiography

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Cardiac Amyloidosis pRevaleNce of in OLDer Subjects Affected by Heart Failure
Plain-language title
Checking how common heart amyloidosis is in very old heart failure patientsGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
20 April 2026