Care bundle tested for brain bleeds caused by spontaneous intracerebral hemorrhage
Tests a structured care bundle against standard care in adults with brain bleeding.
Plain-language title generated from the registry record
Registry title: International Care Bundle Evaluation in Cerebral Hemorrhage Research
Key facts
- Where
- Eksjö, Gothenburg, Hässleholm, Helsingborg, Huddinge, Jönköping, Kalmar, Karlskrona, Karlstad, Köping, Kristianstad, Kungälv, Linköping, Ljungby, Lund, Malmö, Mölndal, Örebro, Oskarshamn, Östersund, Skövde, Stockholm, Sundsvall, Trollhättan, Umeå, Uppsala, Varberg, Värnamo, Västerås, Vaxjo, and Ystad, SwedenSee the 38 sites
- Phase
- Phase 4
Where in Sweden
- Höglandssjukhuset i EksjöEksjö, SwedenTaking people
- Östra SjukhusetGothenburg, SwedenTaking people
- Sahlgrenska UniversitetssjukhusetGothenburg, SwedenTaking people
- Hässleholms sjukhusHässleholm, SwedenTaking people
- Helsingborgs lasarettHelsingborg, SwedenTaking people
- Karolinska Universitetssjukhuset HuddingeHuddinge, SwedenTaking people
- Lanssjukhuset RyhovJönköping, SwedenTaking people
- Länssjukhuset KalmarKalmar, SwedenTaking people
- BlekingesjukhusetKarlskrona, SwedenTaking people
- Blekingesjukhuset KarlskronaKarlskrona, SwedenTaking people
- Centralsjukhuset KarlstadKarlstad, SwedenTaking people
- Västmanlands sjukhus KöpingKöping, SwedenTaking people
- Centralsjukhuset KristianstadKristianstad, SwedenTaking people
- Kungälvs sjukhusKungälv, SwedenTaking people
- Univeristetssjukhuset LinköpingLinköping, SwedenTaking people
- Ljungby LasarettLjungby, SwedenTaking people
- Skåne University Hospital LundLund, SwedenTaking people
- Skåne University Hospital Lund Neurosurgery deptLund, SwedenTaking people
- Region Skåne, Skåne University Hospital in Malmö, Department of NeurologyMalmö, SwedenTaking people
- Mölndals SjukhusMölndal, SwedenTaking people
- Universitetssjukhuset ÖrebroÖrebro, SwedenTaking people
- Oskarshamn SjukhusOskarshamn, SwedenTaking people
- Östersunds LasarettÖstersund, SwedenTaking people
- Skaraborgs sjukhus SkövdeSkövde, SwedenTaking people
- Capio St Görans sjukhusStockholm, SwedenTaking people
- Danderyds sjukhusStockholm, SwedenTaking people
- Karolinska Universitetssjukhuset SolnaStockholm, SwedenTaking people
- SödersjukhusetStockholm, SwedenTaking people
- Länssjukhuset SundsvallSundsvall, SwedenTaking people
- Norra Älvsborgs LänssjukhusTrollhättan, SwedenTaking people
- Norrlands universitetssjukhusUmeå, SwedenTaking people
- Akademiska Sjukhuset UppsalUppsala, SwedenTaking people
- Lasarettet i EnköpingUppsala, SwedenTaking people
- Hallands sjukhus VarbergVarberg, SwedenTaking people
- Värnamo sjukhusVärnamo, SwedenTaking people
- VästeråsVästerås, SwedenTaking people
- Centrallasarettet VäxjöVaxjo, SwedenTaking people
- Ystads lasarettYstad, SwedenTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Region Skane
- Trial code
- NCT06429332
- Record updated
- 22 May 2026
- Original description
Spontaneous intracerebral haemorrhage (ICH) accounts for approximately 10-15% of all strokes but stands for 50% of stroke-related morbidity and mortality. Approximately half of all patients with ICH have a decreased level of consciousness at hospital admission. Despite this, intensive care and neurosurgical interventions are uncommon. A study conducted in low- and middle-income countries has demonstrated a beneficial effect of a treatment package consisting of early intensive blood pressure lowering, as well as the treatment of pyrexia and elevated blood glucose levels. The I-CATCHER team is now planning to conduct a similar study in Sweden and Australia, as well as in other high-income countries. The study has a clear focus on implementation, aiming to improve treatment and prognosis for patients with ICH within a few years. The purpose of I-CATCHER is to investigate whether a structured treatment package (Care Bundle) improves 3-month prognosis in patients with spontaneous ICH compared to standard care.Read full original descriptionShow less
International Care Bundle Evaluation in Cerebral Hemorrhage Research - a Batched Parallel Cluster-randomized Trial With a Baseline Period
Spontaneous intracerebral haemorrhage (ICH) accounts for approximately 10-15% of all strokes but stands for 50% of stroke-related morbidity and mortality. Approximately half of all patients with ICH have a decreased level of consciousness at hospital admission. Despite this, intensive care and neurosurgical interventions are uncommon. A study conducted in low- and middle-income countries has demonstrated a beneficial effect of a treatment package consisting of early intensive blood pressure lowering, as well as the treatment of pyrexia and elevated blood glucose levels. The I-CATCHER team is now planning to conduct a similar study in Sweden and Australia, as well as in other high-income countries. The study has a clear focus on implementation, aiming to improve treatment and prognosis for patients with ICH within a few years. The purpose of I-CATCHER is to investigate whether a structured treatment package (Care Bundle) improves 3-month prognosis in patients with spontaneous ICH compared to standard care.
Inclusion: Adults (age ≥18 years); Non-contrast computerized tomography (NCCT) imaging-verified diagnosis of spontaneous intracerebral haemorrhage; ≤24 hours from symptom onset or presumed symptom onset (last seen well).
Exclusion: Previous care limitation; End-stage comorbidity with short life-expectancy (<6 m; e.g. terminal cancer); ICH caused by brain tumor or cerebral venous thrombosis; Clinical signs of brain herniation at first presentation (unresponsive patient with bilaterally fixed, maximally dilated pupils); Pregnant women beyond 22 weeks gestation may only be included after thorough discussion with an obstetrician to determine risks vs benefit.