Long-term study following people with a first episode of schizophrenia in Denmark
Follows people newly diagnosed with schizophrenia spectrum disorder, and some at high risk, over time.
Plain-language title generated from the registry record
Registry title: The Danish Region Midt Schizophrenia Cohort
Key facts
- Where
- Aarhus, Herning, Horsens, Randers, and Silkeborg, DenmarkSee the 5 sites
Where in Denmark
- Aarhus University Hospital PsychiatryAarhus, DenmarkTaking people
- Psychiatric Hospital GødstrupHerning, DenmarkTaking people
- Psychiatric Hospital HorsensHorsens, DenmarkTaking people
- Psychiatric Hospital RandersRanders, DenmarkTaking people
- Psychiatric Hospital MidtSilkeborg, DenmarkTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Aarhus
- Trial code
- NCT06431009
- Record updated
- 29 May 2024
- Original description
The objective of this study is to recruit patients at the first diagnosis with a schizophrenia spectrum disorder (SSD) and ultra-high risk patients (UHR), defined as patients with drug abuse and psychotic symptoms indicating a risk for developing schizophrenia. Thereby, the investigators aim to establish a large representative cohort of patients with a first-episode SSD or patients at UHR, enabling investigations of the etiology and long-term prognosis of SSDs. The primary aim is to learn more about the importance of adverse childhood experiences (ACEs) and the immune system in the etiology and course of schizophrenia. Patients will be followed with planned visits after 1, 2, 3, 12 and 24 months including online questionnaires after 2, 6, 10 and 26 weeks. There will be the possibility to contact patients again for subsequent follow-up visits.Read full original descriptionShow less
The Danish Region Midt Schizophrenia (RMS) Cohort: Representative Cohort of Patients With a First-episode Schizophrenia Spectrum Disorder With Long-term Follow-up
The objective of this study is to recruit patients at the first diagnosis with a schizophrenia spectrum disorder (SSD) and ultra-high risk patients (UHR), defined as patients with drug abuse and psychotic symptoms indicating a risk for developing schizophrenia. Thereby, the investigators aim to establish a large representative cohort of patients with a first-episode SSD or patients at UHR, enabling investigations of the etiology and long-term prognosis of SSDs. The primary aim is to learn more about the importance of adverse childhood experiences (ACEs) and the immune system in the etiology and course of schizophrenia. Patients will be followed with planned visits after 1, 2, 3, 12 and 24 months including online questionnaires after 2, 6, 10 and 26 weeks. There will be the possibility to contact patients again for subsequent follow-up visits.
Inclusion: Age ≥15 years; Diagnosed within the previous 3 months with first-episode SSD (ICD-10: F20-29) or UHR (ICD-10: F1X.5); Able to give informed oral and written consent.
Exclusion: In a clinical condition where the treating clinician evaluates that the patient is not able to attend the research study; Any coercive measure including patients in forensic psychiatry.