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Taking people in SwedenNo phase

Studying why some heart failure patients respond better to treatment

Observational study collecting samples from adults with heart failure to find biomarkers.

Key facts

Who runs it
Karolinska University Hospital
Where
Stockholm, SwedenSee the site
Trial code
Registry title
Responders and Non-responders in the Management of Heart Failure - Significance of Genetic Influence and Identification of Novel Informative Biomarkers
Status
Recruiting
People taking part
5,000 people, planned
Started
17 Feb 2021
Expected to end
31 Dec 2030
Type of study
Observational
Record updated
10 August 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with heart failure who are registered in the Swedish heart failure registry SwedeHF and give written consent.

Age
18 years or older
Sex
All sexes can join.
Disease stage
Heart failure with symptoms and signs of heart failure, as judged by the local investigator.

Main reasons for not taking part

  • Plasma donation within 1 month before joining
  • Blood donation or blood loss of more than 500 mL in the 3 months before joining
  • Previous bone marrow transplant from another person
  • A condition that could put the patient at risk or affect the results, in the investigator's opinion

The registry criteria, word for word

Show all 6 criteriaShow less

Who can take part

  • Written informed consent
  • Heart failure defined by symptoms and signs of heart failure as judged by the local investigator
  • Registered in SwedeHF

Who cannot take part

  • Plasma donation within 1 month of enrolment or any blood donation/blood loss >500 mL during the 3 months prior to enrolment
  • Previous allogeneic bone marrow transplant (genetics)
  • In the opinion of the investigator, condition/s that may either put the patient at risk on participation or influence the results or the patient's ability to participate in the study

Where in Sweden

  • Karolinska University HospitalStockholm, SwedenContact: Camilla Hage, Ass profTaking people

About the trial

What the trial wants to find out

A biobank within the Swedish national heart failure quality registry SwedeHF.

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Responders and Non-responders in the Management of Heart Failure - Significance of Genetic Influence and Identification of Novel Informative Biomarkers
Plain-language title
Studying why some heart failure patients respond better to treatmentGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Publications
Record updated
10 August 2026