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Brain Activity Patterns in Parkinson's Disease During Movement

Studies brain electrical activity during simple movements in people with Parkinson's disease.

Key facts

Who runs it
University Hospital, Bordeaux
Where
Bordeaux, FranceSee the site
Trial code
Registry title
Parkinsonism-Related Oscillations in the Cortico-Basal Ganglia-Thalamic Network During Movement: Beyond the Frequency Range
Status
Recruiting
People taking part
20 people, planned
Started
16 Apr 2025
Expected to end
Apr 2027
Type of study
Interventional
Treatments tested
  • Electrophysiological recordings
Record updated
2 May 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults aged 18 to 75 with idiopathic Parkinson's disease who have a deep brain stimulation device (STN-DBS with PERCEPT) or are about to get one.

Age
18 to 75 years
Sex
All sexes can join.
Disease stage
Idiopathic Parkinson's disease.
Earlier treatment
Has had an STN-DBS with a PERCEPT device for less than a year, or is a candidate for a first implantation of this device.

Main reasons for not taking part

  • Cannot give consent personally
  • Under a legal protection measure (curatorship, guardianship or judicial protection)
  • Pregnant or breastfeeding
  • Serious and/or decompensated physical or psychiatric illness

The registry criteria, word for word

Show all 11 criteriaShow less

Who can take part

  • Male or Female
  • 18 to 75 years-old
  • With idiopathic Parkinson's disease
  • Having a STN-DBS with a PERCEPT™ for less than a year or being candidate for STN-DBS with the PERCEPT™ device (first-implantation)
  • Able to perform the simple motor task
  • Patients covered by a health insurance scheme
  • Giving free, informed, written consent signed by the participant and the investigator

Who cannot take part

  • Present a serious and/or decompensated somatic or psychiatric illness
  • Be incapable of giving consent personally
  • Be subject to a legal protection measure (curatorship, guardianship) or be placed under judicial protection
  • Being pregnant or breastfeeding

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 75 years old?

Where in France

  • Bordeaux University HospitalBordeaux, FranceContact: Dominique Guehl, PrTaking people

About the trial

What the trial wants to find out

Expression of hypokinetic and hyperkinetic motor symptoms in Parkinson's disease (PD) is associated with pathological synchronous oscillations of neuronal activity (local field potential/LFP) in the cortico-subcortical network with a wide frequency range. In the present project, we propose to study cortico-subcortical oscillations and their synchronization in patients operated for PD (subthalamic deep brain stimulation (STN-DBS)) during distinct pharmacological and stimulation conditions (hypokinetic and hyperkinetic), using a simple motor task.

The group in the trial

  • Recruited patientTreatment being tested

    Patient with idiopathic Parkinson's disease and having a STN DBS with a PERCEPT™ for less than a year or being candidate for subthalamic nucleus deep brain stimulation with the PERCEPT™ device (first-implantation)

    Treatment: Electrophysiological recordings

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Parkinsonism-Related Oscillations in the Cortico-Basal Ganglia-Thalamic Network During Movement: Beyond the Frequency Range
Plain-language title
Brain Activity Patterns in Parkinson's Disease During MovementGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Fit questions
Built from NCT06438419, who can take part
Record updated
2 May 2025