Effects of THC on Alcohol Consumption and Neural Correlates of Reward
Key facts
- Who runs it
- University of Colorado, Denver
- Where
- Aurora, United StatesSee the site
- Trial code
- Status
- Recruiting
- Phase
- Phase 2
- People taking part
- 28 people, planned
- Started
- 1 Jul 2024
- Planned end
- 30 Jun 2026
- Type of study
- Interventional, 2 groups
- Treatments tested
- Dronabinol Pill
- Placebo
- Record updated
- 19 August 2024
Who can take part
- Age
- 21 years to 40 years
- Sex
- Women and men
- Healthy volunteers
- Can take part
The registry criteria, word for word
Show all 5 criteriaShow less
Who can take part
- Drink alcohol
- Use cannabis
- Contact site for additional details
Who cannot take part
- MRI contraindications (implanted metal, weight > 315 lb, etc.)
- Contact site for additional details
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 21 and 40 years old?
Where in United States
- University of Colorado Anschutz Medical CampusAurora, United StatesContact: Elnaz Nourollahimoghadam, MDTaking people
About the trial
What the trial wants to find out
Alcohol and cannabis are often used together such that their effects overlap, but little is known about the neural mechanisms that underlie simultaneous use. High doses of THC have not been well-studied in the laboratory, and it is unclear how high doses of THC may impact alcohol consumption patterns. The proposed study will explore the effects of oral THC (20mg dronabinol) vs. placebo on neural reward, alcohol self-administration and naturalistic co-use patterns.
The 2 groups in the trial
- Placebo first, Dronabinol secondTreatment being tested
This arm will receive placebo on the first visit, and dronabinol on the second visit
Treatment: Dronabinol Pill and Placebo
- Dronabinol first, Placebo secondTreatment being tested
This arm will receive dronabinol on the first visit, and placebo on the second visit.
Treatment: Dronabinol Pill and Placebo
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Fit questions
- Built from NCT06446479, who can take part
- Record updated
- 19 August 2024