Exercise Training Study of Patients With Claudicatio Intermittens
Key facts
- Who runs it
- Norwegian University of Science and Technology
- Where
- Norway and Sweden14 sites in 2 countriesChoose a country to see its sites
- Trial code
- Status
- Recruiting
- People taking part
- 100 people, planned
- Started
- 1 Jan 2024
- Planned end
- 31 Dec 2025
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Physical training
- Record updated
- 6 June 2025
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 20 criteriaShow less
Who can take part
- Pain in the calves after 300 m, or less measured on a treadmill
- Stable symptoms last 6 months or more
- The pain must be gone within 5 minutes after the patients stop walking
- Ankle-Brachial index at 0.7 or lower at rest
- Using statins and antiplatelet drugs since at least 3 months
- age> 18 years
- Signed consent
Who cannot take part
- Use of statins and antiplatelet drugs less than 3 months
- General conditions that impairs the ability to take part in a training study including Obesity, KOLS, heart disease, arthrosis, inflammatory joint diseases
- Diabetes measured with HbA1c being over 48 mmol/mol (6%)
- Age less than 18 years
- pain in the hips or elsewhere outside the calves while walking
- Remaining pain more than 5 minutes after stopped walking
- Impossible to compress the arteries while measruing ABI or ABI lower than 0.4
- symptoms less than 6 months
- Revascularisation the last 6 months
- Pain in the calves after longer than 300 m measured on a treadmill
- Reduced mobility in the ankles
- Reduced physical ability to perform a test on a treadmill
- No Signed consent
This trial has no sites in United States.
It has sites in 2 countries. Choose a country to see its sites.
About the trial
What the trial wants to find out
The aim of the study is to evaluate whether walking capacity in patients with intermittent claudication is improved more by home-based 5+ exercise training than by current recommendations of daily walking.
The 2 groups in the trial
- Five plus trainingExisting treatment, for comparison
During "five plus training" the participants are standing in front of a wall, which is used for support of the balance. The body is lifted with the calf musculature to the maximal height that the subject can achieve. This is repeated until pain is felt in the calf musculature. Following the initiation of pain the subject performs five extra repetitions. The five extra calf raises are included to secure induction of ischemia followed by reperfusion to secure maximal training effect.
Treatment: Physical training
- walkingExisting treatment, for comparison
Walking at least 30 minutes three times per week.
Treatment: Physical training
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Randomized Clinical Trial on the Effects of Home-based Five Plus Exercise Training
- Record updated
- 6 June 2025