Mobile Applet for Weight Management in Obese Heart Failure Patients
Key facts
- Where
- Anshan, Beijing, Changzhi, Diaobingshancun, Guangzhou, Jixi, Kaifeng, Langfang, Luoyang, Pingdu, Shangqiu, Shenyang, Taian, Taizhou, Tongliao, Ürümqi, Weihai, Xian, Xinyang, Yulin, and Zhengzhou, ChinaSee the 26 sites
Where in China
- Xiu Yan Manchu Autonomous County Central People's HospitalAnshan, ChinaTaking people
- Beijing Anzhen HospitalBeijing, ChinaTaking people
- Beijing Chuiyangliu HospitalBeijing, ChinaNot yet recruiting
- Beijing Fangshan District First HospitalBeijing, ChinaTaking people
- Emergency General HospitalBeijing, ChinaNot yet recruiting
- Qin Yuan County People's HospitalChangzhi, ChinaTaking people
- Tiemei General Hospital of Liaoning Health Industry GroupDiaobingshancun, ChinaNot yet recruiting
- Guangzhou Red Cross HospitalGuangzhou, ChinaTaking people
- Jixi City People's HospitalJixi, ChinaTaking people
- Kaifeng Central HospitalKaifeng, ChinaNot yet recruiting
- Langfang People's HospitalLangfang, ChinaTaking people
- Luoyang No.6 People's HospitalLuoyang, ChinaTaking people
- Ruyang County People's HospitalLuoyang, ChinaTaking people
- Pingdu People's HospitalPingdu, ChinaTaking people
- Ningling County People's HospitalShangqiu, ChinaTaking people
- Yongcheng People's HospitalShangqiu, ChinaTaking people
- Shenyang Tenth HospitalShenyang, ChinaTaking people
- Taian First HospitalTaian, ChinaTaking people
- Yuhuan Second People's HospitalTaizhou, ChinaNot yet recruiting
- Tongliao People's HospitalTongliao, ChinaTaking people
- The First Affiliated Hospital of Xinjiang Medical UniversityÜrümqi, ChinaTaking people
- Weihai Central HospitalWeihai, ChinaNot yet recruiting
- Xian Red Cross HospitalXian, ChinaTaking people
- Shangcheng County People's HospitalXinyang, ChinaTaking people
- The First Affiliated Hospital of Xi'an Jiaotong University, Yulin Branch HospitalYulin, ChinaTaking people
- Henan Provincial Chest HospitalZhengzhou, ChinaNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Heart Health Research Center
- Trial code
- NCT06455878
- Record updated
- 27 June 2025
- Original description
The objective of this clinical trial is to investigate the effect of weight reduction through a diet management application and an intelligent weight scale on a composite cardiovascular endpoint in obese patients with heart failure.Read full original descriptionShow less
The Impact of Dietary Management Applet for Weight Reduction in Obese Heart Failure Patients: a Multicenter, Single-blind Randomized Controlled Trial
The objective of this clinical trial is to investigate the effect of weight reduction through a diet management application and an intelligent weight scale on a composite cardiovascular endpoint in obese patients with heart failure.
The main questions are:
Does the use of a diet management APP and intelligent weight scale reduce 1-year all-cause mortality, heart failure hospitalization, and first heart failure hospital stay? Does the use of a diet management APP and intelligent weight scale improve the outcomes of assessment of heart failure frailty and quality of life for heart failure?
Researchers will compare using the fully functional diet management app and intelligent weight scale to using the limitedly functional app and intelligent weight scale to see if the app works to improve heart failure conditions.
Participants will:
Use the diet management app at every meal and the intelligent weight scale every day for 12 months, and visit the clinic at 12 months for checkups.
Inclusion: Age ≥18 years; Left ventricular ejection fraction (LVEF) ≤ 50%, with New York Heart Association (NYHA) class II-III; Body mass index (BMI) ≥ 26 kg/m² or male waist-to-hip ratio (WHR=waist circumference/hip circumference) ≥ 0.9, female waist-to-hip ratio ≥ 0.85; Ability to use a smartphone and demonstrate compliance via a diet management mobile application during a 2-week ±1-week run-in period; History of heart failure hospitalization within the past 6 months; Signed informed consent.
Exclusion: Current use of weight-loss medications or planned bariatric surgery; Concurrent participation in another interventional clinical study; End-stage heart failure (≥2 hospitalizations for heart failure in the past 3 months, intolerance to guideline-directed medical therapy (GDMT), or dependence on inotropic agents); Heart failure with reversible causes (e.g., peripartum cardiomyopathy, fulminant myocarditis); Uncontrolled thyroid disease (hyperthyroidism/hypothyroidism) or end-stage liver failure; Malignancy with an expected survival <1 year; Conditions potentially hindering protocol compliance, as judged by the investigator (e.g., habitual reliance on food delivery services or company cafeteria meals); Moderate or severe anemia (hemoglobin [Hb] <90 g/L); Renal insufficiency (estimated glomerular filtration rate [eGFR] <30 mL/min/1.73 m²) or ongoing dialysis; Alcohol or substance abuse; Planned hospitalization during the trial period.