Observes outcomes in people with relapsed or refractory acute myeloid leukemia
Follows people with acute myeloid leukemia that has returned or not responded to treatment.
Plain-language title generated from the registry record
Registry title: Master Framework For Relapse or Refractory Acute Myeloid Leukemia
Key facts
- Where
- Ancona, Bologna, Brescia, Brindisi, Busto Arsizio, Castelfranco Veneto, Como, Cremona, Cuneo, Ferrara, Florence, Genova, Meldola, Milan, Naples, Novara, Padova, Palermo, Perugia, Pescara, Ravenna, Rimini, Roma, Salerno, Torino, and Vicenza, ItalySee the 32 sites
Where in Italy
- Azienda Ospedaliero-Universitaria delle MarcheAncona, ItalyTaking people
- Policlinico Sant'Orsola-MalpighiBologna, ItalyTaking people
- ASST Spedali CiviliBrescia, ItalyTaking people
- Ospedale A. PerrinoBrindisi, ItalyTaking people
- ASST Valle OlonaBusto Arsizio, ItalyTaking people
- IOV Istituto Oncologico VenetoCastelfranco Veneto, ItalyTaking people
- Ospedale ValduceComo, ItalyTaking people
- ASST CremonaCremona, ItalyTaking people
- Azienda Ospedaliera S. Croce e CarleCuneo, ItalyTaking people
- AOU Universitaria Arcispedale Sant'AnnaFerrara, ItalyTaking people
- AOU CareggiFlorence, ItalyTaking people
- IRCCS Ospedale Policlinico San MartinoGenova, ItalyTaking people
- IRST Istituto Romagnolo per lo Studio dei Tumori Dino AmadoriMeldola, ItalyTaking people
- ASST Grande Ospedale Metropolitano NiguardaMilan, ItalyTaking people
- Fondazione IRCCS Cà Granda Ospedale Maggiore PoliclinicoMilan, ItalyTaking people
- Azienda Ospedaliera di Rilievo Nazionale Antonio CardarelliNaples, ItalyTaking people
- Azienda Ospeldaliera Universitaria Federico IINaples, ItalyTaking people
- AOU "Maggiore della Carità"Novara, ItalyTaking people
- Azienda Ospedale Universita PadovaPadova, ItalyTaking people
- Azienda Ospedaliera Ospedali Riuniti Villa Sofia - CervelloPalermo, ItalyTaking people
- Ospedale Santa Maria della MisericordiaPerugia, ItalyTaking people
- Presidio Ospedaliero "Santo Spirito"Pescara, ItalyNot yet recruiting
- Ospedale Santa Maria delle CrociRavenna, ItalyTaking people
- Ospedale "Infermi" di RiminiRimini, ItalyTaking people
- Fondazione Policlinico Tor VergataRoma, ItalyTaking people
- Ospedale Sant'AndreaRoma, ItalyTaking people
- Policlinico Umberto IRoma, ItalyTaking people
- Policlinico Universitario Fondazione Agostino GemelliRoma, ItalyTaking people
- AOU "San Giovanni di Dio e Ruggi d'Aragona"Salerno, ItalyTaking people
- AO Ordine MaurizianoTorino, ItalyTaking people
- AOU Città della Salute e della Scienza di TorinoTorino, ItalyTaking people
- Ospedale San BortoloVicenza, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
- Trial code
- NCT06459024
- Record updated
- 27 October 2026
- Original description
This is an observational (non-interventional), prospective, cohort study that will collects data from patients diagnosed with relapsed or refractory acute myeloid leukemia afferent to the participanting clinical sitesRead full original descriptionShow less
Master Framework For Relapse or Refractory Acute Myeloid Leukemia- IMPACT STREAM - A Prospective Observational Study of Treatment Outcomes
This is an observational (non-interventional), prospective, cohort study that will collects data from patients diagnosed with relapsed or refractory acute myeloid leukemia afferent to the participanting clinical sites
Inclusion: Patients with AML diagnosis according to WHO2022 or ICC2022; Treatment failure (i.e. relapse, refractory or progression, including MRD) according to ELN2022 criteria; Participant or his/her legal representative is willing and able to give informed consent for participation in the study.
Exclusion: Patients included in clinical trials may be enrolled except where otherwise specified in the experimental protocol.