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Testing a Brief Talk Therapy for People With Advanced Ovarian Cancer

Tests a brief talk therapy, CALM, in adults with newly diagnosed or recurrent ovarian cancer.

Plain-language title generated from the registry record
Registry title: Feasibility of CALM in Patients With Ovarian Cancer

Key facts

Where
Toronto, CanadaSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adult women with newly diagnosed or recurrent stage III or IV ovarian cancer. It tests a short talking therapy called CALM.

Age
18 years or older
Sex
Women only
Disease stage
New diagnosis or recurrence of stage III or stage IV ovarian cancer
Earlier treatment
Not receiving psychological or psychiatric counseling from the Department of Supportive Care at PM at the time of recruitment

Main reasons for not taking part

  • Signs of cognitive impairment
  • Receiving psychological or psychiatric counseling from the Department of Supportive Care at PM at the time of recruitment
  • Cannot complete the measures and take part in CALM in English

Read by machine on 9 November 2026.

Where in Canada

  • Princess Margaret Cancer CentreToronto, CanadaTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Trial details

Who runs it
University Health Network, Toronto
Trial code
NCT06459271
Record updated
24 August 2026
Original description
The goal of this feasibility trial is to determine the feasibility and acceptability of implementing a brief evidence-based psychotherapeutic intervention, Managing Cancer And Living Meaningfully (CALM), at the time of a new diagnosis and recurrence of ovarian cancer (OC).Read full original descriptionShow less

A Feasibility Trial of Managing Cancer and Living Meaningfully (CALM) in Patients With Newly Diagnosed and Recurrent Advanced Ovarian Cancer

The goal of this feasibility trial is to determine the feasibility and acceptability of implementing a brief evidence-based psychotherapeutic intervention, Managing Cancer And Living Meaningfully (CALM), at the time of a new diagnosis and recurrence of ovarian cancer (OC).

The main questions are:

1. Is it feasible and acceptable to implement CALM for patients with newly diagnosed or recently recurred advanced OC 2. What is the patient experience of CALM-TF at new diagnosis or recurrence

Participants will be asked to complete questionnaires at baseline and at 3 and 6 months following a diagnosis or recurrence of stage III or IV OC. Participants will also be invited to participate in 3-6 sessions of CALM therapy.

Inclusion: new diagnosis or recurrence of stage III or stage IV OC; age ≥18 years; able to complete outcome measures and engage in CALM in English.

Exclusion: receiving psychological or psychiatric counseling from the Department of Supportive Care at PM at the time of recruitment; evidence of cognitive impairment indicated in the medical record, communicated by the OC clinic team, or determined by research staff at recruitment.

ClinicalTrials.gov NCT06459271