App-based thinking and movement training for young people with cancer
Tests the Mio-App, a thinking and physical training app, in children with cancer.
Plain-language title generated from the registry record
Registry title: Metacognitive Intervention in Youth With Oncological Disease - the Mio Study
Key facts
- Where
- Bern, SwitzerlandSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 8 and 16 years old?
Source: NCT06464237, who can take part
Where in Switzerland
- Insespital, University Hospital BernBern, SwitzerlandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Insel Gruppe AG, University Hospital Bern
- Trial code
- NCT06464237
- Record updated
- 26 November 2025
- Original description
The aim of the Mio-Study is to address the current lack of effective treatment options to reduce cognitive and physical long-term problems in children and adolescents with cancer. Through the use of the Mio-App, cognitive and physical development will be strengthened and metacognitive thinking and awareness will increase.Read full original descriptionShow less
Metacognitive Intervention in Youth With Oncological Disease - the Mio Study
The aim of the Mio-Study is to address the current lack of effective treatment options to reduce cognitive and physical long-term problems in children and adolescents with cancer. Through the use of the Mio-App, cognitive and physical development will be strengthened and metacognitive thinking and awareness will increase.
The Mio-App for children and adolescence with cancer will include a combination of cognitive and physical training tasks and prospective as well as retrospective metacognitive questions. In a randomized controlled trial, the App will be analysed for its efficacy on metacognitive thinking and executive functions. In particular, the investigators are interested in factors that affect the efficacy of the training program such as compliance, age, sex or the presence of fatigue. This study will give insight into the role of metacognition in cognitive and physical performance and will foster the development of children and adolescents with cancer in the long-term.
Inclusion: Informed consent as documented by signature (see Informed Consent Form) of participants and / or parents / legal guardians; Age 8-16 years; A diagnosis of cancer either with or without CNS involvement. The participant will be included between 3 months before to 10 years after termination of treatment; Treatment of cancer including either radiation, chemotherapy and/ or surgical tumor removal; German or French speaking.
Exclusion: Drug or alcohol abuse; Any other instable neurological condition (e.g. epilepsy); A severe psychiatric disease (e.g., eating disorder) or severe learning disability; Known or suspected non-compliance; Inability to follow the procedures of the study, e.g. due to language problems; Enrolment of the investigator, his/her family members, employees and other dependent persons.