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Self-applied acupressure for dry mouth in head and neck cancer

Tests self-applied acupressure for dry mouth in adults with head and neck cancer.

Plain-language title generated from the registry record
Registry title: Acupressure on Xerostomia in Head and Neck Cancer Patients

Key facts

Where
Hong Kong, Hong KongSee the site

Where in Hong Kong

  • Queen Mary HospitalHong Kong, Hong KongTaking people

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Trial details

Who runs it
The University of Hong Kong
Trial code
NCT06465628
Record updated
28 May 2025
Original description
This is a randomized controlled trial aimed to1) examine the effect of a self-administered acupressure intervention on head and neck cancer patients with xerostomia (primary outcome) relative to oral health education control; 2) examine the effect of self-administered acupressure on secondary outcomes, including quality of life and severity of symptoms of head and neck cancer patients; 3) evaluate patients' expectancy of acupressure; 4) explore the acceptability of self-administered acupressure for head and neck cancer patients with xerostomia.Read full original descriptionShow less

Effect of Self-administered Acupressure for Improving Xerostomia in Head and Neck Cancer Patients: a Randomized Controlled Trial

This is a randomized controlled trial aimed to1) examine the effect of a self-administered acupressure intervention on head and neck cancer patients with xerostomia (primary outcome) relative to oral health education control; 2) examine the effect of self-administered acupressure on secondary outcomes, including quality of life and severity of symptoms of head and neck cancer patients; 3) evaluate patients' expectancy of acupressure; 4) explore the acceptability of self-administered acupressure for head and neck cancer patients with xerostomia.

Hypothesis: self-administered acupressure has better effect on xerostomia for head and neck cancer patients comparing to oral health education. Acupressure will also benefit head and neck cancer patients on quality of life and severity of symptoms. Head and neck cancer patients may have good acceptability of self-administered acupressure.

Inclusion: age ≥18 years; able to give informed consent; diagnosed with head and neck cancer (cancers in the head and neck region, e.g. oral cancer, nasopharyngeal cancer, oropharyngeal cancer, hypopharyngeal cancer, laryngeal cancer, sinus cancer, salivary gland cancer); completed radiation therapy or chemoradiotherapy for at least 2 weeks; complains of xerostomia after the treatment; able to communicate in Cantonese or Mandarin.

Exclusion: history of xerostomia prior to head and neck cancer treatment (e.g., Sjögren Syndrome); practiced acupressure or received acupuncture in the last 3 months; having contraindications to acupressure, e.g. blood system disease (e.g., leukemia); pregnancy; lactating; upper or lower extremity deformities; infection or injuries at the acupoints; Those who are taking medications/alternative substances to treat xerostomia on a fixed dosage regimen in the past one month will not be excluded; -.

ClinicalTrials.gov NCT06465628