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Taking people in RussiaNo phase

Studies adults with uncontrolled severe asthma across Russia

Observes adults with hard-to-control severe asthma, without changing their usual treatment.

Key facts

Who runs it
AstraZeneca
Where
Astrakhan, Barnaul, Blagoveshchensk, Bryansk, Chelyabinsk, Gatchina, Irkutsk, Izhevsk, Kazan', Kemerovo, Khabarovsk, Krasnodar, Krasnoyarsk, Moscow, Murmansk, Nal'chik, Nizhny Novgorod, Novosibirsk, Omsk, Orenburg, Petrozavodsk, Rostov-on-Don, Ryazan, Saint Petersburg, Samara, Saratov, Smolensk, Stavropol, Tomsk, Ufa, Ulan-Ude, Verkhnyaya Pyshma, Vladimir, Vladivostok, Volgograd, Voronezh, Yakutsk, and Yekaterinburg, RussiaSee the 38 sites
Trial code
Registry title
Clinical and demOgRaphic Features of Patients With Uncontrolled Severe Asthma in Russia (CORSAR)
Status
Recruiting
People taking part
5,000 people, planned
Started
6 Jun 2024
Expected to end
30 Jun 2027
Type of study
Observational
Record updated
6 October 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with uncontrolled severe asthma who are treated in routine care and have at least 52 weeks of medical records.

Age
18 years or older
Sex
All sexes can join
Disease stage
Uncontrolled severe asthma (ACQ-5 score above 1.5), diagnosed at least 52 weeks before joining. Asthma stays uncontrolled despite medium or high dose inhaled steroids plus other asthma medicines, taken for at least 3 months.
Earlier treatment
Must not have had any biological therapy now or in the 52 weeks before joining. Must have used the standard asthma treatment for at least 3 months.

Main reasons for not taking part

  • Biological therapy now or in the last 52 weeks
  • COPD or idiopathic pulmonary fibrosis now or in the past
  • Taking part in another clinical study now or in the last 52 weeks
  • An illness that the investigator thinks limits taking part or affects the results

The registry criteria, word for word

Show all 8 criteriaShow less

Who can take part

  • Age ≥ 18 years at the time of inclusion
  • Signed and dated written informed consent in accordance with ICH GCP and local law prior to inclusion in the study
  • Patients with diagnosis of uncontrolled SA (Asthma Control Questionnaire-5 (ACQ-5) score > 1,5) established no less than 52 weeks prior to inclusion; Severe asthma is defined as asthma, that is controlled due to treatment with ICS in medium or high doses plus LABA and/or ALP, and/or LAMA, and/or systemic corticosteroids (sCS), and/or immunobiological therapy, while attempts to reduce the volume of therapy lead to a loss of symptom control, or asthma remains uncontrolled despite this treatment. Such therapy should be carried out at least 3 months before inclusion; Uncontrolled asthma is defined as ACQ-5>1.5
  • Patients with the availability of at least 52 weeks of follow-up data (prior to inclusion) in the medical records

Who cannot take part

  • Patients receiving any biological therapy currently or within 52 weeks prior to inclusion
  • The participation in any clinical study currently or within 52 weeks prior to inclusion
  • Presence of chronic obstructive pulmonary disease (COPD) or idiopathic pulmonary fibrosis (ILF) currently or in the anamnesis
  • An acute or chronic disease that, as deemed by Investigator, limits the ability of patients to participate in this study or could influence the interpretation of the results

Where in Russia

  • AstrakhanHospital not named in the registryTaking people
  • BarnaulHospital not named in the registryTaking people
  • BlagoveshchenskHospital not named in the registryTaking people
  • BryanskHospital not named in the registryTaking people
  • ChelyabinskHospital not named in the registryTaking people
  • GatchinaHospital not named in the registryTaking people
  • IrkutskHospital not named in the registryTaking people
  • IzhevskHospital not named in the registryTaking people
  • Kazan'Hospital not named in the registryTaking people
  • KemerovoHospital not named in the registryTaking people
  • KhabarovskHospital not named in the registryTaking people
  • KrasnodarHospital not named in the registryNo longer taking part
  • KrasnoyarskHospital not named in the registryTaking people
  • MoscowHospital not named in the registryTaking people
  • MurmanskHospital not named in the registryTaking people
  • Nal'chikHospital not named in the registryTaking people
  • Nizhny NovgorodHospital not named in the registryTaking people
  • NovosibirskHospital not named in the registryTaking people
  • OmskHospital not named in the registryTaking people
  • OrenburgHospital not named in the registryTaking people
  • PetrozavodskHospital not named in the registryTaking people
  • Rostov-on-DonHospital not named in the registryTaking people
  • RyazanHospital not named in the registryTaking people
  • Saint PetersburgHospital not named in the registryTaking people
  • SamaraHospital not named in the registryTaking people
  • SaratovHospital not named in the registryTaking people
  • SmolenskHospital not named in the registryNo longer taking part
  • StavropolHospital not named in the registryTaking people
  • TomskHospital not named in the registryTaking people
  • UfaHospital not named in the registryTaking people
  • Ulan-UdeHospital not named in the registryTaking people
  • Verkhnyaya PyshmaHospital not named in the registryTaking people
  • VladimirHospital not named in the registryTaking people
  • VladivostokHospital not named in the registryTaking people
  • VolgogradHospital not named in the registryTaking people
  • VoronezhHospital not named in the registryTaking people
  • Yakutsk, Sakha RepublicHospital not named in the registryTaking people
  • YekaterinburgHospital not named in the registryTaking people

About the trial

What the trial wants to find out

This study is an observational multicenter cross-sectional study. Planned study population consists of 5 000 adult patients with uncontrolled SA receiving treatment according to standard of care (except biologics). Planned number of study site is 50 outpatient centers with experience of uncontrolled SA treatment in about 50 regions of Russia (in order to describe characteristics of patients with uncontrolled SA in different regions in the most comprehensive way). This non-interventional study does not imply any intervention into a routine clinical practice, and does not provide for any diagnostic and therapeutic procedures other than those used in routine practice.

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
An Observational Multicenter Cross-sectional Study of Patients With Uncontrolled Severe Asthma in the Population of the Russian Federation
Plain-language title
Studies adults with uncontrolled severe asthma across RussiaGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
6 October 2026