Studying vaginal bacteria in women with and without vaginal conditions
Collects vaginal swabs to study bacteria in women with common vaginal and urinary infections.
Plain-language title generated from the registry record
Registry title: Vaginal Ecosystem and Network in the United States Study
Key facts
- Where
- Alexandria, Bethesda, Bryn Mawr, Corvallis, Easton, Fullerton, Henderson, Honolulu, Kenmore, Los Angeles, Mayfield Heights, New York, Oklahoma City, Pasadena, Portland, Shenandoah, Tulsa, Virginia Beach, and Winston-Salem, United StatesSee the 20 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 89 years old?
Source: NCT06472765, who can take part
Where in United States
- Empowered Midwifery and Wellness LLCAlexandria, United StatesNo longer taking part
- Rachel Rubin MD PLLCBethesda, United StatesNo longer taking part
- Center for Pelvic MedicineBryn Mawr, United StatesNo longer taking part
- Center of the HealthCorvallis, United StatesNo longer taking part
- Dr. Christina Enzmann at Easton Advanced Aesthetics and Regenerative MedicineEaston, United StatesNo longer taking part
- Women's Pelvic Health CenterFullerton, United StatesNo longer taking part
- Xena HealthHenderson, United StatesNo longer taking part
- Healthy Mothers, Healthy Babies Coalition of HawaiiHonolulu, United StatesNo longer taking part
- Empire OBGYNKenmore, United StatesNo longer taking part
- Claris HealthLos Angeles, United StatesNo longer taking part
- University of California Los Angeles Department of Radiation OncologyLos Angeles, United StatesNo longer taking part
- UH HospitalsMayfield Heights, United StatesNo longer taking part
- Gary H Goldman, MDNew York, United StatesNo longer taking part
- Northwest Obstetrics and GynecologyOklahoma City, United StatesNo longer taking part
- Pelvic Pain RehabPasadena, United StatesNo longer taking part
- Amber Wellness GroupPortland, United StatesNo longer taking part
- North Houston Gynecologic Oncology Surgeons, PLLCShenandoah, United StatesNo longer taking part
- Haven Center for Sexual Medicine & Vulvovaginal DisordersTulsa, United StatesNo longer taking part
- Hello ClimaxVirginia Beach, United StatesNo longer taking part
- Camel City Women's WellnessWinston-Salem, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Vaginal Biome Science
- Trial code
- NCT06472765
- Record updated
- 1 July 2025
- Original description
The central premise of this study is that the intricate balance and diversity of the vaginal microbiome plays a pivotal role in the onset, progression, and severity of various gynecological conditions. Specifically, the research aims to investigate how imbalances in microbial communities, such as the overgrowth of pathogenic bacteria or the depletion of beneficial ones, are linked to conditions like Bacterial Vaginosis, Candidiasis, Urinary Tract Infections, Vaginal Atrophy, and others. By employing PCR testing and the outcomes of next-generation sequencing (NGS) of the microbiome, the study seeks to identify distinct microbial profiles and patterns that are characteristic of each condition. This nuanced understanding is expected to lead to more accurate and early diagnosis, facilitating personalized and effective treatment strategies that go beyond the conventional, often indiscriminate use of antibiotics.Read full original descriptionShow less
Comprehensive Registry and PCR Analysis of the Vaginal Microbiome in Women: Data Collection in Healthy and Diseased States
The central premise of this study is that the intricate balance and diversity of the vaginal microbiome plays a pivotal role in the onset, progression, and severity of various gynecological conditions. Specifically, the research aims to investigate how imbalances in microbial communities, such as the overgrowth of pathogenic bacteria or the depletion of beneficial ones, are linked to conditions like Bacterial Vaginosis, Candidiasis, Urinary Tract Infections, Vaginal Atrophy, and others. By employing PCR testing and the outcomes of next-generation sequencing (NGS) of the microbiome, the study seeks to identify distinct microbial profiles and patterns that are characteristic of each condition. This nuanced understanding is expected to lead to more accurate and early diagnosis, facilitating personalized and effective treatment strategies that go beyond the conventional, often indiscriminate use of antibiotics.
Inclusion: Healthy cis-gender women between ages 18 and 89.
Exclusion: Pregnant or trying to conceive (i.e. IVF, IUI).