NCT06475027Not yet recruiting
Exosome-miRNA and Transcriptome Profiling of Dry Eye Syndrome and Sjogren's Syndrome
Systematic Dissection of Exosome-miRNA and Transcriptome Profiling of Dry Eye Syndrome and Sjogren's Syndrome for Alleviating the Sicca Symptoms
Source: ClinicalTrials.gov · Last updated 26 Jun 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study combines data from two trials testing acupuncture (ACUDES) and a Chinese herbal tea bag TBDESJS for Dry Eye Syndrome and Sjögren's syndrome. Both treatments improved tear production. Researchers will now analyze participants' blood remaining samples and other data to understand how these therapies work. They will use advanced methods to identify tiny RNA molecules and immune system activity. This integrated approach aims to explain how acupuncture and TBDESJS improve dryness and support their use in managing these conditions.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 220 (estimated)
- First submitted
- 11 Jun 2024
- Start date
- 1 Jul 2024
- Primary completion date
- 1 Oct 2024
- Lead sponsor
- Taipei Veterans General Hospital, Taiwan
- Diseases
- Sjögren's disease
- NCT number
- NCT06475027
What you commit to
- Study type: Observational
- Planned participants: 220
- From 1 Jul 2024 to the primary completion date, 1 Oct 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Dry eye syndrome
- Inclusion Criteria: aged between 20 and 75 years Schirmer's test less than 10 mm/5 min
- Exclusion Criteria: Pregnancy With eye inflammation or infectious eye disease Accepted operation of eye
- Sjögren's syndrome
- Inclusion Criteria: primary or secondary SS aged between 20 and 75 years fulfilled the 2002 American-European Consensus Criteria for SS (AECG) had no abnormal findings of immune, liver, kidney, or blood function evaluations.
- Exclusion Criteria: a history of alcohol abuse, diabetes mellitus, or major life-threatening condition pregnancy or breastfeeding steroid pulse therapy within three months prior to the commencement of our study.
- non AIDDES Healthy Controls
- Inclusion Criteria: aged between 20 and 75 years without any Chronic disease
- Exclusion Criteria: any Sjögren's syndrome or Dry eye syndrome.
Age in the registry: 20 years to 75 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ching-Mao Chang Coordinator of this site? Confirm its status | Taipei | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.