Tests a camera pill against standard colonoscopy for bowel disease checks
Tests a swallowed camera capsule in adults with symptoms of colorectal disease.
Plain-language title generated from the registry record
Registry title: Camera Capsule Endoscopy in the Routine Diagnostic Pathway for Colorectal Diseases
Key facts
- Where
- Odense C, DenmarkSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with symptoms who were referred for a colonoscopy. It tests a camera capsule swallowed to look at the bowel, instead of a standard colonoscopy.
- Age
- Older than 18 years
- Sex
- All sexes can join
- Disease stage
- Symptomatic patients referred for colonoscopy assessment
- Earlier treatment
- Cannot join if they had a colonoscopy with poor bowel preparation within the last 5 years, or major surgery of the digestive tract with an internal derivation or a stoma
Main reasons for not taking part
- Needs hospital admission for an inpatient colonoscopy
- History of narrowing (stenosis) of the digestive tract
- Has a pacemaker or defibrillator
- Is pregnant or breastfeeding
- Has severe kidney disease or known chronic constipation
Read by machine on 9 November 2026.
Where in Denmark
- Odense University HospitalOdense C, DenmarkTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Odense University Hospital
- Trial code
- NCT06475560
- Record updated
- 19 March 2026
- Original description
The Department of Surgery at Odense University Hospital (OUH) carries out approximately 10,000 colonoscopies each year, and this number is continuously increasing. Since 2014, the screening for colorectal cancer (CRC) has resulted in a significant increase in the colonoscopy workload. Conventional colonoscopy (CC) is a hospital-based procedure that can require sedation or analgesics and is often considered uncomfortable, intimidating, or even painful. The diagnostic yield of CC can be as low as 3-5% in some patient groups, which means that an endoscopist may need to perform 20 to 30 colonoscopies to identify one case requiring treatment. Physical or cultural barriers can also deter patients from attending appointments, leading to missed cancers or precancerous lesions. To address these challenges, an alternative pathway is needed to reduce the colonoscopy burden on the healthcare system while ensuring fewer findings are missed.Read full original descriptionShow less
Camera Capsule Endoscopy in the Routine Diagnostic Pathway for Colorectal Diseases
The Department of Surgery at Odense University Hospital (OUH) carries out approximately 10,000 colonoscopies each year, and this number is continuously increasing. Since 2014, the screening for colorectal cancer (CRC) has resulted in a significant increase in the colonoscopy workload. Conventional colonoscopy (CC) is a hospital-based procedure that can require sedation or analgesics and is often considered uncomfortable, intimidating, or even painful. The diagnostic yield of CC can be as low as 3-5% in some patient groups, which means that an endoscopist may need to perform 20 to 30 colonoscopies to identify one case requiring treatment. Physical or cultural barriers can also deter patients from attending appointments, leading to missed cancers or precancerous lesions. To address these challenges, an alternative pathway is needed to reduce the colonoscopy burden on the healthcare system while ensuring fewer findings are missed.
One solution is to use Colon Capsule Endoscopy (CCE) as a triage tool. This procedure can be performed in outpatient healthcare centers and requires less equipment than an CC. However, CCE offers no therapeutic capability, and individuals with clinically significant findings will still require an CC. A low reinvestigation rate (<25%-30%) is desirable for patient preference and the economy.
Therefore, DanCap will introduce a new pathway that relies on CCE for routine colorectal examinations of symptomatic patients who are expected to have a low rate of positive findings and, consequently, a low reinvestigation rate, and asses the cost of this new pathway.
Inclusion: Older than 18 years; Symptomatic patient referred for colonoscopy assessment; Able to provide oral and written informed consent.
Exclusion: Previous OC with poor bowel preparation within the last 5 years; Previous major surgery of the digestive tract with consequence of an internal derivation or a stoma*; History of stenosis of the digestive tract; Known allergies to the bowel preparation regimen; Have severe kidney disease; Require hospital admission for inpatient colonoscopy; Patient is unable to provide oral and written informed consent; Patient has a pacemaker/defibrillator; Patient is pregnant or breastfeeding; Known chronic constipation; Imaging examination suggestive for a colorectal tumour; Anamnestic suspicion of microscopic colitis, where biopsy is needed *including Whipple.