Under construction – not a live service
Sign in
Taking peopleNo phase

Homologus PRP in the Infiltrative Treatment of Knee Osteoarthritis in Young Athletic Patients

Key facts

Who runs it
Istituto Ortopedico Rizzoli
Where
Italy1 site in 1 countryChoose a country to see its sites
Trial code
Status
Recruiting
People taking part
30 people, planned
Started
10 Oct 2023
Planned end
Sept 2026
Type of study
Interventional
Treatments tested
  • PRP infiltration
Record updated
4 July 2025

Who can take part

Age
18 years to 40 years
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 18 criteriaShow less

Who can take part

  • Patients, both sexes, with symptomatic knee osteoarthritis with:
  • Age: 18-40 years
  • Unilateral involvement
  • Signs and symptoms of knee osteoarthritis
  • Radiographic or MRI signs of degenerative pathology of knee cartilage (Kellgren-Lawrence grade 1-3)
  • Ability and consent of patients to actively participate in clinical follow-up
  • Signature of informed consent
  • Pain ≥ 4 on VAS s

Who cannot take part

  • Patients undergoing intra-articular infiltration of other substance in the previous 6 months
  • Patients undergoing knee surgery in the previous 12 months
  • Patients abusing alcoholic beverages, drugs or medications
  • Knee trauma treated in the previous 6 months
  • Patients with malignant neoplasms
  • Patients with rheumatic diseases
  • Patients with uncontrolled metabolic diseases
  • Patients with hematological diseases (coagulopathies)
  • Other conditions that may interfere with the evaluation of OA treatment
  • Patients unable to express consent

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 40 years old?

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

The study consists of 3 phases (enrollment, infiltrative procedure, and controls):

Read full original descriptionShow less

* Identification by specialized orthopedic medical staff belonging to the SC Orthopedic and Trauma Clinic II of the Rizzoli Orthopedic Institute of subjects who meet the study inclusion criteria. Signing of informed consent form and completion of evaluation questionnaires. * infiltrative procedure * Patients will be clinically evaluated before the infiltration procedure and at 1, 3, 6, and 12 months after treatment by trained medical personnel (outcome assessors). Questionnaires will be administered for clinical evaluations before treatment and at these clinical checkups during follow-up. Any adverse events to treatment will also be assessed during follow-up visits. The duration and extent of joint swelling and pain following infiltration will be reported, and any drug therapies taken by the patient will be recorded.

The group in the trial

  • infiltrative procedureOther group

    Treatment: PRP infiltration

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Fit questions
Built from NCT06483269, who can take part
Record updated
4 July 2025