Tests a heart procedure during cardiac surgery in adults without atrial fibrillation
Tests a pericardiotomy procedure in adults without atrial fibrillation having heart surgery.
Plain-language title generated from the registry record
Registry title: Pericardiotomy in Cardiac Surgery
Key facts
- Where
- Innsbruck and Vienna, AustriaSee the 2 sites
Where in Austria
- Medical University of InnsbruckInnsbruck, AustriaTaking people
- Medical University ViennaVienna, AustriaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Population Health Research Institute
- Trial code
- NCT06486636
- Record updated
- 21 October 2026
- Original description
PRINCE is an international, multicentre, randomized controlled trial of posterior pericardiotomy in patients without a history of atrial fibrillation (AF) or flutter undergoing cardiac surgery.Read full original descriptionShow less
Pericardiotomy in Cardiac Surgery Trial
PRINCE is an international, multicentre, randomized controlled trial of posterior pericardiotomy in patients without a history of atrial fibrillation (AF) or flutter undergoing cardiac surgery.
Inclusion: Patients greater than or equal to 18 years of age; Requiring surgical intervention on the proximal aorta, cardiac valves, and/or coronary arteries; Able to provide informed consent.
Exclusion: Prior cardiac surgery requiring opening of the pericardium; Previous surgical instrumentation of the left pleural cavity; History of atrial fibrillation or flutter; Cardiac surgery procedures not included in the inclusion criteria (planned ventricular assistance device, planned aortic arch, transplantation surgery); Patient undergoing minimally invasive cardiac surgery.