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Studying how the brain makes goal-directed decisions in people with epilepsy

Records single brain cell activity during a decision task in adults with epilepsy.

Plain-language title generated from the registry record
Registry title: Neural Computations of Goal-directed Decision-making

Key facts

Where
Los Angeles, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 65 years old?

Source: NCT06489561, who can take part

Where in United States

  • Cedars-Sinai Medical CenterLos Angeles, United StatesNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Cedars-Sinai Medical Center
Trial code
NCT06489561
Record updated
23 July 2026
Original description
The purpose of this research is to better understand how the human brain accomplishes the cognitive task of making goal-directed decisions. These investigations are critical to better understand human cognition and to design treatments for disorders of decision making and performance monitoring.Read full original descriptionShow less

Probing the Neural Computations Underlying Goal-directed Decision-making in Humans With Single-neuron Recordings

The purpose of this research is to better understand how the human brain accomplishes the cognitive task of making goal-directed decisions. These investigations are critical to better understand human cognition and to design treatments for disorders of decision making and performance monitoring.

Inclusion: Intractable epilepsy, undergoing invasive monitoring; Age ≥13; Full Scale Intelligence Quotient > 70; Ability to comprehend and perform simple behavioral tasks by pressing buttons on laptop computer in response to questions.

Exclusion: Determination by clinicians and investigators that a patient is unable to complete the behavioral tasks required for the protocol due to either cognitive limits, psychological limits, or pain.

ClinicalTrials.gov NCT06489561