Coding of Speech Signals in the Human Auditory Nerve
Key facts
- Where
- Reims, FranceSee the site
Where in France
- Damien JOLLYReims, FranceContact: Xavier DUBERNARDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- CHU de Reims
- Trial code
- NCT06490237
- Record updated
- 8 July 2024
- Original description
The fine evaluation of the function of auditory neurons in silence and in noise in humans is difficult, if not impossible, to date with the conventional methods available. That is why in certain situations, the hearing aids of patient with hearing loss fail, especially in the presence of noise.Read full original descriptionShow less
Coding of Speech Signals in the Human Auditory Nerve - an Exploratory Study
The fine evaluation of the function of auditory neurons in silence and in noise in humans is difficult, if not impossible, to date with the conventional methods available. That is why in certain situations, the hearing aids of patient with hearing loss fail, especially in the presence of noise.
In this study the investigators aim at investigating the global spontaneous and sound evoked human auditory nerve activity from electrophysiological acquisitions performed directly on the cochlear nerve in patients requiring posterior fossa surgery.
Inclusion: Will be included as hearing impaired patients:; male or female; over 18 years of age; who are to undergo surgery on the cerebellopontine angle (microvascular decompression, vestibular neurotomy, removal of a meningioma or schwannoma tumor); with a mild to severe sensorineural hearing loss defined by an average hearing loss (average of thresholds obtained at 500, 1000, 2000 and 4000 Hz) greater than 20 dB and less than 90 dB in pure tone bone conduction audiometry on the side of the operated ear; affiliated to a social security system; have read the information note describing the study and have agreed in writing to participate by signing the informed consent form; Will be included as normal hearing patients:; male or female; over 18 years of age; who are to undergo surgery in the cerebellopontine angle (microvascular decompression, vestibular neurotomy, removal of a meningioma or schwannoma tumor); free of neuro-sensory deafness, defined by average hearing thresholds less than or equal to 20 dB in tonal bone conduction audiometry on the side of the operated ear; affiliated with a social security system; having read the information note describing the study and having agreed in writing to participate by signing the informed consent form.
Exclusion: Patients for whom the auditory nerve is not accessible during surgery,; because of a complete tumor invasion of the cochlear nerve (stage III and IV neuroma, advanced meningioma); because of an anatomical feature not identified during the preoperative examination, making its exposure for recordings impossible (protrusion of the posterior face of the rock).