Comparing Light and Moderate Exercise for Myasthenia Gravis Patients
Tests light versus moderate exercise in adults with myasthenia gravis, a neuromuscular disease.
Plain-language title generated from the registry record
Registry title: Light vs. Moderate Intensity Exercise in Individuals With Myasthenia Gravis
Key facts
- Where
- Saint Paul, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT06491238, who can take part
Where in United States
- HealthPartners Neuroscience CenterSaint Paul, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- HealthPartners Institute
- Trial code
- NCT06491238
- Record updated
- 23 March 2026
- Original description
The overall purpose of this pilot study is to examine the feasibility, acceptability, and tolerability of light and moderate intensity exercise in adults with MGeffect of light vs. moderate intensity exercise on health outcomes. Participants will be enrolled into the NeuroWell exercise program, which is geared toward individuals with neurological disorders or injuries and led by Certified Exercise Physiologists (CEPs) at the HealthPartners Neuroscience Center. A total of 20 people with MG will be enrolled in this study and participate in a small group exercise program 3 times a week for 12 weeks. Participants will be randomized into two exercise groups: 1) Light intensity or 2) Moderate intensity. We hypothesize that light and moderate intensity exercise will be feasible, acceptable, and tolerable in adults with MG and that individuals in the light intensity exercise group will be able to achieve the same improvement in health outcomes as the moderate intensity group.Read full original descriptionShow less
Light vs. Moderate Intensity Exercise in Individuals With Myasthenia Gravis
The overall purpose of this pilot study is to examine the feasibility, acceptability, and tolerability of light and moderate intensity exercise in adults with MGeffect of light vs. moderate intensity exercise on health outcomes. Participants will be enrolled into the NeuroWell exercise program, which is geared toward individuals with neurological disorders or injuries and led by Certified Exercise Physiologists (CEPs) at the HealthPartners Neuroscience Center. A total of 20 people with MG will be enrolled in this study and participate in a small group exercise program 3 times a week for 12 weeks. Participants will be randomized into two exercise groups: 1) Light intensity or 2) Moderate intensity. We hypothesize that light and moderate intensity exercise will be feasible, acceptable, and tolerable in adults with MG and that individuals in the light intensity exercise group will be able to achieve the same improvement in health outcomes as the moderate intensity group.
Inclusion: Ability to provide and provision of signed and dated informed consent form; Age 18-80; Diagnosis of generalized MG; On a stable MG prescription medication regimen for the last 3 months.
Exclusion: Regular exercise participation within the month prior to study enrollment or any outside exercise participation during the study intervention period; Significant cognitive impairment of any etiology that would impact study participation; History of heart failure, chronic lung disease, angina or any other condition that causes unreasonable shortness of breath on exertion; History of any serious neurological, psychiatric, or substance use disorders that would impact study participation; Any other medical conditions that could affect their ability to participate in exercise for the study duration (as determined by study investigators); Non-English speaking; Women who are currently pregnant or planning to become pregnant during the study; Active participation or past participation ≤3 months in any other interventional research study; Unwilling to participate in all study related activities.