Interval Exercise Training for Atrial Fibrillation Patients
Tests two levels of interval exercise training in adults with non-permanent atrial fibrillation.
Plain-language title generated from the registry record
Registry title: Effect of Aerobic Interval Training on Atrial Fibrillation Burden
Key facts
- Where
- Beijing, ChinaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 18 to 74 with non-permanent atrial fibrillation who want to take part in a 12-week exercise programme.
- Age
- 18 to 74 years
- Sex
- All sexes
- Disease stage
- Non-permanent atrial fibrillation, with a resting heart rate of 110 beats per minute or lower.
- Earlier treatment
- No formal exercise prescription in the past six months.
Main reasons for not taking part
- Heart attack, stroke, heart surgery or similar events in the past 6 months
- Heart failure NYHA class III-IV, or severe heart valve disease or other serious heart conditions
- Severe kidney or liver problems, including dialysis
- Pregnancy
- Pacemaker or ICD, or a planned atrial fibrillation ablation during the study
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 74 years old?
Source: NCT06491329, who can take part
Where in China
- Sixth Medical Center of Chinese PLA General HospitalBeijing, ChinaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Navy General Hospital, Beijing
- Trial code
- NCT06491329
- Record updated
- 2 August 2024
- Original description
Atrial fibrillation is the most common arrhythmia, with an increasing incidence and prevalence, significantly increasing the risk of death, stroke, heart failure, cognitive impairment, and dementia, severely impacting the quality of life for patients and burdening society and healthcare systems. In recent years, exercise-based cardiac rehabilitation has gradually become a new approach for the treatment of patients with heart disease. The main research topics include: 1. Changes in atrial fibrillation burden in non-permanent atrial fibrillation patients after 12 weeks of HIIT(high-intensity interval training ) or MIIT (moderate-intensity interval training). 2. Changes in cardiorespiratory fitness, quality of life scores, mental health assessment scores, atrial strain, and left ventricular diastolic function in non-permanent atrial fibrillation patients after 12 weeks of aerobic interval training, along with follow-up on the occurrence of exercise-related adverse events and adverse cardiovascular events during the study period.Read full original descriptionShow less
Effect of Aerobic Interval Training on Atrial Fibrillation Burden：A Multicenter Randomized Controlled Study
Atrial fibrillation is the most common arrhythmia, with an increasing incidence and prevalence, significantly increasing the risk of death, stroke, heart failure, cognitive impairment, and dementia, severely impacting the quality of life for patients and burdening society and healthcare systems. In recent years, exercise-based cardiac rehabilitation has gradually become a new approach for the treatment of patients with heart disease. The main research topics include: 1. Changes in atrial fibrillation burden in non-permanent atrial fibrillation patients after 12 weeks of HIIT(high-intensity interval training ) or MIIT (moderate-intensity interval training). 2. Changes in cardiorespiratory fitness, quality of life scores, mental health assessment scores, atrial strain, and left ventricular diastolic function in non-permanent atrial fibrillation patients after 12 weeks of aerobic interval training, along with follow-up on the occurrence of exercise-related adverse events and adverse cardiovascular events during the study period.
Inclusion: Age range: 18-74 years; Patients with non-permanent atrial fibrillation; Resting heart rate ≤110 beats/min; No history of receiving a formal exercise prescription within the past six months; Willing to participate in this study, provide written informed consent, and agree to comply with follow-up procedures.
Exclusion: Concurrent severe arrhythmias; frequent multifocal premature ventricular contractions; ventricular tachycardia, ventricular fibrillation; high-degree or complete atrioventricular block; ventricular asystole lasting more than 5 seconds; Concurrent cancer or autoimmune or systemic inflammatory disease; History of myocardial infarction, endocarditis/myocarditis/pericarditis, stroke (ischemic/hemorrhagic), pulmonary embolism, lower extremity venous thrombosis, or cardiac surgery within the past 6 months; Moderate to severe pulmonary arterial hypertension, moderate to severe valvular heart disease, hypertrophic cardiomyopathy, aortic stenosis/dilation/dissection/intramural hematoma, congenital heart disease; Heart failure (NYHA class III-IV) or acute exacerbation of heart failure within the past 3 months; Unstable angina or severe coronary artery disease without revascularization; Uncontrolled hypertension or hypotension; Hypoxemia or severe lung disease; Lower extremity arterial stenosis or musculoskeletal disease preventing exercise training; Cognitive impairment preventing study cooperation; Severe anemia, infection, electrolyte disturbances, hyperthyroidism; Severe renal or hepatic dysfunction; Stage 5 chronic kidney disease, defined as glomerular filtration rate <15 ml/(min•1.73 m2) or requiring dialysis; Patient with alanine aminotransferase (ALT) or aspartate aminotransferase (AST) levels greater than or equal to 5 times the upper limit of normal as defined by the center during screening; Intracardiac thrombus; Pregnancy; Planned atrial fibrillation ablation during the study period; Post-implantation of pacemaker or ICD; Inability to use smart devices; Regular moderate-to-high intensity exercise habits (≥2 sessions of high-intensity endurance training per week or ≥3 sessions of moderate-intensity endurance training.