Oral Iron Supplementation on Alternate vs. Consecutive Days for Iron Deficiency Anemia in Pregnancy
Key facts
- Who runs it
- Southern Illinois University
- Where
- Springfield, United StatesSee the site
- Trial code
- Status
- Recruiting
- Phase
- Phase 4
- People taking part
- 120 people, planned
- Started
- 27 May 2025
- Expected to end
- 30 Jul 2029
- Type of study
- Interventional, 2 groups
- Treatments tested
- daily ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill
- alternate day ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill
- Record updated
- 24 April 2026
Who can take part
- Age
- 18 years to 45 years
- Sex
- Women only
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 2 criteriaShow less
Who can take part
- Pregnant patients will be enrolled at less than 30 weeks gestational age (GA) with laboratory confirmed IDA (as defined by hemoglobin under 10.5 g/dL, as well as ferritin under 15 mcg/L)
Who cannot take part
- Patients <18 years old, patients who have severe IDA that requires blood transfusion or IV iron infusion, patients who have other known hemoglobinopathy (such as thalassemia or sickle cell anemia) or anemia of different mechanism (such as vitamin B12 or folate deficiency), patients with ulcerative colitis, Crohn's disease, gastric ulcers, patients who have previously undergone gastric bypass surgery, patients who experience admission for antepartum bleed, have been diagnosed with abnormal placentation (i.e., placenta previa, placenta accreta, placenta increta or percreta)
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 45 years old?
Where in United States
- Southern Illinois University School of MedicineSpringfield, United StatesContact: Amber Fifer, Pharm DTaking people
About the trial
What the trial wants to find out
This will be a randomized clinical trial. Enrolled subjects will be randomized (1:1) into two study arms to receive either daily (Group 1) or alternate day (Group 2) supplementation with one oral pill containing ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill.
The 2 groups in the trial
- 1) Daily dose of ferrous sulfate with an equivalent elemental iron dose of 65 mg per pillTreatment being tested
daily (Group 1) supplementation with one oral pill containing ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill
Treatment: daily ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill
- 2) Alternate daily dose of ferrous sulfate with an equivalent elemental iron dose of 65 mg per pillTreatment being tested
alternate day (Group 2) supplementation with one oral pill containing ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill
Treatment: alternate day ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Fit questions
- Built from NCT06492512, who can take part
- Record updated
- 24 April 2026