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CompletedNo phase

PRISM for Depression and Anxiety in Young Adults With Cancer

Key facts

Who runs it
Dana-Farber Cancer Institute
Where
Brighton, United StatesSee the site
Trial code
Status
Completed
People taking part
13 people enrolled
Started
6 Sept 2024
Ended
1 Feb 2026
Type of study
Interventional
Treatments tested
  • Promoting Resilience in Stress Management Program
Record updated
21 April 2026

Who can take part

Age
18 years to 39 years
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

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Who can take part

  • 18-39 years of age
  • Speak and comprehend English sufficiently to be able to complete study procedures and participate in the program in English*
  • Have been diagnosed with cancer or desmoid tumor at least 6 or more weeks ago
  • Currently receiving treatment or has completed treatment for cancer or desmoid tumor no more than 6 months ago
  • Score 10-24 (with question #9 not endorsed, or 0) on the PHQ-9 (Kroenke et al., 1999) or/and score 10-21 on the GAD-7 (Spitzer et al., 2006) during the initial screening assessment; Participant Exclusion Criteria:
  • Adults unable to consent, individuals who are not yet adults (age <18), pregnant women, and prisoners
  • Individuals who score less than 10 on both PHQ-9 and GAD-7
  • Individuals who are diagnosed with cancer less than 6 weeks at the time of screening (we will be able to approach them again after 6 weeks since diagnosis has passed), or those who completed treatment more than 6 months ago will also be ineligible for this study; they will be offered resources for support, if desired
  • Individuals who report any suicidality (ideation, plan, and/or intent) on PHQ-9 screen (i.e., endorse anything more than 0 for question #9) at the time of the eligibility screening will also be excluded from the current study, and the appropriate safety measures and/or referral to a mental health provider will be made (see section 14.1 for more details on the procedure)
  • -≥ 18 years of age
  • -A friend or family member invited by the study participant to join the 6th PRISM session

Where in United States

  • Dana-Farber Cancer InstituteBrighton, United States

About the trial

What the trial wants to find out

This research study is being done to test the feasibility of an existing supportive program (PRISM) to address psychological symptoms (i.e., depressive and anxiety symptoms) that young adult participants diagnosed with cancer or desmoid tumor may experience.

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The name of the intervention used in this research study is:

-Promoting Resilience in Stress Management (PRISM) Program

The group in the trial

  • PRISM ProgramTreatment being tested

    Participants will be enrolled and will complete study procedures as follows: * Baseline visit with questionnaires. * 6 weekly or bi-weekly remote or in-clinic, psychotherapy sessions with psychologist. * Final questionnaires and post-study exit interview

    Treatment: Promoting Resilience in Stress Management Program

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Treatment Development Study of the Promoting Resilience in Stress Management (PRISM) Intervention for Depression and Anxiety in Young Adults With Cancer
Record updated
21 April 2026