Frontlight ResearchEarly access
CompletedNo phase
PRISM for Depression and Anxiety in Young Adults With Cancer
Key facts
- Who runs it
- Dana-Farber Cancer Institute
- Where
- Brighton, United StatesSee the site
- Trial code
- Status
- Completed
- People taking part
- 13 people enrolled
- Started
- 6 Sept 2024
- Ended
- 1 Feb 2026
- Type of study
- Interventional
- Treatments tested
- Promoting Resilience in Stress Management Program
- Record updated
- 21 April 2026
Who can take part
- Age
- 18 years to 39 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
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Who can take part
- 18-39 years of age
- Speak and comprehend English sufficiently to be able to complete study procedures and participate in the program in English*
- Have been diagnosed with cancer or desmoid tumor at least 6 or more weeks ago
- Currently receiving treatment or has completed treatment for cancer or desmoid tumor no more than 6 months ago
- Score 10-24 (with question #9 not endorsed, or 0) on the PHQ-9 (Kroenke et al., 1999) or/and score 10-21 on the GAD-7 (Spitzer et al., 2006) during the initial screening assessment; Participant Exclusion Criteria:
- Adults unable to consent, individuals who are not yet adults (age <18), pregnant women, and prisoners
- Individuals who score less than 10 on both PHQ-9 and GAD-7
- Individuals who are diagnosed with cancer less than 6 weeks at the time of screening (we will be able to approach them again after 6 weeks since diagnosis has passed), or those who completed treatment more than 6 months ago will also be ineligible for this study; they will be offered resources for support, if desired
- Individuals who report any suicidality (ideation, plan, and/or intent) on PHQ-9 screen (i.e., endorse anything more than 0 for question #9) at the time of the eligibility screening will also be excluded from the current study, and the appropriate safety measures and/or referral to a mental health provider will be made (see section 14.1 for more details on the procedure)
- -≥ 18 years of age
- -A friend or family member invited by the study participant to join the 6th PRISM session
Where in United States
- Dana-Farber Cancer InstituteBrighton, United States
About the trial
What the trial wants to find out
This research study is being done to test the feasibility of an existing supportive program (PRISM) to address psychological symptoms (i.e., depressive and anxiety symptoms) that young adult participants diagnosed with cancer or desmoid tumor may experience.
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The name of the intervention used in this research study is:
-Promoting Resilience in Stress Management (PRISM) Program
The group in the trial
- PRISM ProgramTreatment being tested
Participants will be enrolled and will complete study procedures as follows: * Baseline visit with questionnaires. * 6 weekly or bi-weekly remote or in-clinic, psychotherapy sessions with psychologist. * Final questionnaires and post-study exit interview
Treatment: Promoting Resilience in Stress Management Program
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Treatment Development Study of the Promoting Resilience in Stress Management (PRISM) Intervention for Depression and Anxiety in Young Adults With Cancer
- Record updated
- 21 April 2026