Freezing and later returning ovarian tissue for young women with cancer
Tests freezing ovarian tissue, then transplanting it back, in girls and young women with cancer.
Key facts
- Who runs it
- Chinese University of Hong Kong
- Where
- Hong Kong, Hong KongSee the site
- Trial code
- Registry title
- Ovarian Tissue Cryopreservation and Subsequent Auto-Transplantation for Female Cancer Patients (HKCH)
- Status
- Recruiting
- People taking part
- 100 people, planned
- Started
- 13 Aug 2024
- Expected to end
- 31 Jul 2041
- Type of study
- Interventional
- Treatments tested
- Ovarian Tissue Cryopreservation and Subsequent Auto-Transplantation
- Record updated
- 8 January 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for girls and young women with cancer, or with another illness or treatment that may harm their fertility. Ovarian tissue is frozen to preserve fertility.
- Age
- The registry lists 12 Years to 18 Years, while the criteria text says 0-35 years old.
- Sex
- Female only.
- Disease stage
- Diagnosed with cancer, for example leukaemia, lymphoma, bone tumours, neurological neoplasms or sarcoma; or an illness or treatment that may cause irreversible damage to fertility.
Main reasons for not taking part
- No anticipated oncologic therapies
- Pregnant
- Children with one ovary
- Children deemed high risk for perioperative complications
- Unable to provide consent or assent
The registry criteria, word for word
Show all 5 criteriaShow less
Who can take part
- Patients aged from 0-35 years old and diagnosed with cancer e.g., leukaemia, myeloproliferative or myelodysplastic diseases, lymphoma, bone tumours, neurological neoplasms and sarcoma, Paediatric bone marrow transplant patients
- Patients with any illness or who will undergo any type of treatment that may cause irreversible damage to their fertility, such as extensive abdominal surgery, high toxicity medication and treatments
- Patients suffering from hormone-sensitive malignancies who will undergo medical treatment, such as radiotherapy and chemotherapy that is liable to damage their ovaries and deter them from conception in the future
Who cannot take part
- Patients with no anticipated oncologic therapies Patients who are pregnant Children with one ovary Children deemed high risk for perioperative complications Patients unable to provide consent/assent (i.e. significant psychiatric problems/cognitive delay)
- -
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 12 and 18 years old?
Where in Hong Kong
- Hong Kong Children's HospitalHong Kong, Hong KongContact: Elaine NG, MPhilTaking people
About the trial
What the trial wants to find out
Ovarian tissue freezing is an ideal option for these patients as it can be performed immediately and does not need any time for ovarian stimulation. We hope we can develop this service in our locality to allow more young female cancer patients to have their fertility preserved.
The group in the trial
- ovarian tissue freezing and subsequent auto-transplantation after thawingTreatment being tested
Removal of the ovarian tissue will be retrieved via laparoscopic surgery under general anesthesia. The ovarian cortical tissue obtained will be transferred on ice to the laboratory for cryopreservation. After medical treatment, if the patient would like to start a family but has experienced premature ovarian failure, she will have ovarian tissue auto-transplantation after thawing.
Treatment: Ovarian Tissue Cryopreservation and Subsequent Auto-Transplantation
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Ovarian Tissue Cryopreservation and Subsequent Auto-Transplantation for Female
- Plain-language title
- Freezing and later returning ovarian tissue for young women with cancerGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT06505057, who can take part
- Record updated
- 8 January 2026