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Comparing two types of resistance exercise and fatigue in multiple sclerosis

Compares two leg exercise types and their effect on fatigue in people with multiple sclerosis.

Plain-language title generated from the registry record
Registry title: Eccentric Exercise and Fatigue in Multiple Sclerosis

Key facts

Where
New York, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 75 years old?

Source: NCT06505421, who can take part

Where in United States

  • Hunter College, Physical Therapy Department, City University of New YorkNew York, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Hunter College of City University of New York
Trial code
NCT06505421
Record updated
17 July 2024
Original description
The goal of this observational study is to compare the impact of eccentric resistance training to traditional resistance training on fatigue in persons with multiple sclerosis (MS). The primary question this study is asking is the following: is eccentric resistance training more fatiguing than traditional resistance training in persons with MS?. Participants will be asked to come for two sessions for two weeks. In the first week, subjects will undergo a bout of either traditional or eccentric resistance training. The next day they will return to assess their level of fatigue. The following week the subject will return and undergo whatever type of training they did not experience the first week, and it's effects on fatigue will again be assessed. The difference between the subjects level of fatigue for either condition will be compared.Read full original descriptionShow less

The Effect of Lower Extremity Eccentric Resistance Training on Fatigue in Multiple Sclerosis

The goal of this observational study is to compare the impact of eccentric resistance training to traditional resistance training on fatigue in persons with multiple sclerosis (MS). The primary question this study is asking is the following: is eccentric resistance training more fatiguing than traditional resistance training in persons with MS?. Participants will be asked to come for two sessions for two weeks. In the first week, subjects will undergo a bout of either traditional or eccentric resistance training. The next day they will return to assess their level of fatigue. The following week the subject will return and undergo whatever type of training they did not experience the first week, and it's effects on fatigue will again be assessed. The difference between the subjects level of fatigue for either condition will be compared.

Inclusion: Definitive diagnosis of Multiple Sclerosis; Ability to walk for 6 minutes continuously with or without assistive device; Ability read, understand and sign and informed consent.

Exclusion: Evidence of recent exacerbation in the last 2 months prior to starting the study; Orthopedic, cardiopulmonary, or non -MS neurologic condition that could interfere with carrying out the study protocol.

ClinicalTrials.gov NCT06505421