Genetic and Epigenetic Background of Inner Ear Dysfunction in Turner Syndrome
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Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Source: NCT06507007, who can take part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Gødstrup Hospital
- Trial code
- NCT06507007
- Record updated
- 11 September 2026
- Original description
The goal of this case-control study is to pave the way for new revolutionary treatment measures within hearing loss that could either replace or delay the need for hearing aids. The study focuses on people with Turner syndrome (TS).Read full original descriptionShow less
The goal of this case-control study is to pave the way for new revolutionary treatment measures within hearing loss that could either replace or delay the need for hearing aids. The study focuses on people with Turner syndrome (TS).
The aim is to find out if there are specific DNA methylation patterns and/or RNA expression profiles linked to sensorineural hearing loss (SNHL) in people with TS. Additionally, the structure and function of the inner ear in these individuals will be examined to see if there is a connection to their epigenetic profile.
The main question it aims to answer is: Does epigenetics constitute a common denominator for some of the unexplained SNHL cases?
Turner Syndrome (TS) represents an ideal model for studying epigenetics related to sensorineural hearing loss (SNHL).
Participants will undergo the following tests:
* Ear examinations * Hearing tests * Balance tests * Blood tests * MRI scans * CBCT (cone-beam computed tomography) scans
Inclusion: age between 18 and 60 years old.
Exclusion: Use of medication that is known to influence inner ear function; Serious medical disorders; Neurological or psychiatric disorders of any kind; Contraindications for the MRI or CBCT; Medical history with dizziness or hearing problems (controls only).